Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606983 | 0.87 | KDM4E (0.57) | KDM4EGRM1MAPTNPC1RAB9A | |
| SCHEMBL3603304 | 0.86 | NPC1 (0.68) | KDM4EL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL3602994 | 0.85 | MAPT (0.59) | KDM4EL3MBTL1MAPTP4HTMNPC1 | |
| SCHEMBL3602131 | 0.83 | GCK (0.58) | KDM4EL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6985089 | 0.82 | KDM4E (0.69) | KDM4EL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL4887357 | 0.81 | SMN1; SMN2 (0.55) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23742077 | 0.81 | CA1 (0.55) | KDM4EL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL3594123 | 0.80 | SMN1; SMN2 (0.78) | KDM4EL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL8696917 | 0.79 | KDM4E (0.77) | KDM4EGRM1L3MBTL1MAPTRAB9A | |
| SCHEMBL6799313 | 0.79 | RAB9A (0.60) | KDM4EL3MBTL1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | disclosed |
| EP-1963290-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007051560-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | AADAC, HDHD5, HRH4 | KDM4E 1342/4885GRM1 1905/4885L3MBTL1 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.