Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30356248 | 1.00 | ALDH1A1 (0.63) | ALDH1A1GAALMNAMCL1MAPK1 | |
| SCHEMBL16127143 | 0.87 | ALDH1A1 (0.62) | ALDH1A1GAALMNAMCL1KMT2A | |
| SCHEMBL10393407 | 0.86 | ALDH1A1 (0.82) | ALDH1A1GAALMNAMAPK1ALOX12 | |
| SCHEMBL1791238 | 0.84 | GAA (0.73) | ALDH1A1GAALMNAMCL1TDP1 | |
| SCHEMBL31527868 | 0.84 | GAA (0.73) | ALDH1A1GAALMNAMCL1TDP1 | |
| SCHEMBL10396561 | 0.84 | KMT2A (0.53) | ALDH1A1GAALMNAMCL1KMT2A | |
| SCHEMBL5146313 | 0.83 | GAA (0.61) | ALDH1A1GAALMNAMCL1TDP1 | |
| SCHEMBL29654196 | 0.80 | ALDH1A1 (0.64) | ALDH1A1GAALMNAALOX12KMT2A | |
| SCHEMBL1396138 | 0.80 | ALDH1A1 (0.64) | ALDH1A1GAALMNAALOX12KMT2A | |
| SCHEMBL744526 | 0.80 | GAA (0.67) | ALDH1A1GAALMNAMCL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2695970-B1 | FINISHING AGENT FOR TRIVALENT CHROMIUM CHEMICAL CONVERSION COATING FILM, AND METHOD FOR FINISHING BLACK TRIVALENT CHROMIUM CHEMICAL CONVERSION COATING FILM | DIPSOL CHEM (JP) | 2020-03-04 | — | — | EP | disclosed |
| EP-2672819-B1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-11-29 | — | — | EP | disclosed |
| US-9567453-B2 | Finishing agent for trivalent chromium chemical conversion coating film, and method for finishing black trivalent chromium chemical conversion coating film | DIPSOL CHEMICALS CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9107413-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2015-08-18 | — | — | US | disclosed |
| US-9018388-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-9018136-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-8916183-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-12-23 | — | — | US | disclosed |
| US-20140315721-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-10-23 | — | — | US | disclosed |
| WO-2014152213-A2 | COUMARIN DERIVATIVES AND METHODS OF USE IN TREATING CYSTIC FIBROSIS, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, AND MISFOLDED PROTEIN DISORDERS | DISCOVERYBIOMED, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| US-8815922-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-08-26 | — | — | US | disclosed |
| WO-2012109125-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-16 | — | — | WO | disclosed |
| US-20120202687-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC | 2012-08-09 | — | — | US | disclosed |
| US-20100022592-A1 | THIAZOLE DERIVATIVES AS MODULATORS OF G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2010-01-28 | — | — | US | disclosed |
| US-20100022592-A1 | THIAZOLE DERIVATIVES AS MODULATORS OF G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2010-01-28 | — | — | US | disclosed |
| EP-2121675-A1 | THIAZOLE DERIVATIVES AS MODULATORS OF G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008103500-A1 | THIAZOLE DERIVATIVES AS MODULATORS OF G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008103500-A1 | THIAZOLE DERIVATIVES AS MODULATORS OF G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2008-08-28 | — | — | WO | disclosed |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
| US-4252963-A | CYCLIZATION OF PHENYLTHIOUREAS WITH THIONYL CHLORIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315721-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | CYP19A1, CYP1A1, AR | ALDH1A1 588/4885GAA 3750/4885LMNA 3954/4885 |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | ALDH1A1 2069/4885GAA 266/4885LMNA 2932/4885 |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | ALDH1A1 2036/4885GAA 484/4885LMNA 3391/4885 |
| US-20100022592-A1 | THIAZOLE DERIVATIVES AS MODULATORS OF G PROTEIN-COUPLED RECEPTORS | GPR119, GPR65, GPR180 | ALDH1A1 1885/4885GAA 2917/4885LMNA 4346/4885 |
| US-20120202687-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | CYP19A1, CYP1A1, AR | ALDH1A1 588/4885GAA 3750/4885LMNA 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.