Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | SCN4A | P35499 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570918 | 0.93 | AXL (0.49) | AXLGFERCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL361030 | 0.80 | KHK (0.40) | KHKKMT2A | |
| SCHEMBL25604312 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TP53RAB9AGAA | |
| SCHEMBL210148 | 0.80 | AXL (0.60) | AXLGFERCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL29801372 | 0.80 | AXL (0.60) | AXLGFERCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL5679365 | 0.80 | SCN4A (0.49) | AXLGFERCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL25607091 | 0.77 | CYP11B2 (0.39) | CYP3A4ALDH1A1LMNACYP2C9KHK | |
| SCHEMBL360416 | 0.74 | CA2 (0.41) | SMN1; SMN2ALDH1A1RAB9AKHKNPC1 | |
| SCHEMBL26189895 | 0.74 | MAOB (0.40) | MAPT | |
| SCHEMBL19709634 | 0.74 | AXL (0.53) | AXLGFERCYP3A4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |