SCHEMBL360245

SCHEMBL360245

[CH2]c1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
CDC25B P30305 1/20 0.57
NPC1 O15118 7/20 0.56
RAB9A P51151 7/20 0.56
ALDH1A1 P00352 6/20 0.56
SMN1; SMN2 Q16637 6/20 0.56
MAPK1 P28482 5/20 0.56
TP53 P04637 2/20 0.56
CYP3A4 P08684 2/20 0.56
ELANE P08246 1/20 0.56
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
BCL2 P10415 1/20 0.54
MCL1 Q07820 1/20 0.54
LMNA P02545 4/20 0.50
PLA2G1B P04054 3/20 0.50
ATG4B Q9Y4P1 3/20 0.50
MAPT P10636 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28691954 0.79 PTPRC (0.39) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL28260408 0.79 MEN1 (0.92) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL28141482 0.76 MEN1 (0.86) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL4283294 0.76 MEN1 (0.86) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL29358690 0.76 MEN1 (1.00) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL14943 0.76 MEN1 (1.00) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL1901249 0.76 MEN1 (1.00) MEN1KMT2ACDC25BNPC1RAB9A
SCHEMBL28863139 0.75 NPC1 (0.68) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL21834979 0.73 MEN1 (0.80) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL20299926 0.73 MEN1 (0.92) MEN1KMT2ACDC25BNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005100482-A1 COMPOSITIONS BASED ON SILANE-TERMINATED POLYMERS AND HARDENED BY RADIATION AND HUMIDITY, PRODUCTION AND USE THEREOF HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-10-27 WO claimed
US-11180523-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags QUANTUMDX GROUP LIMITED (GB) 2021-11-23 US disclosed
US-10759824-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags QUANTUMDX GROUP LIMITED (GB) 2020-09-01 US disclosed
US-10646416-B2 Microcapsules containing a gas-releasing photolabile compound and uses thereof FIRMENICH SA (CH) 2020-05-12 US disclosed
US-20190248827-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS QUANTUMDX GROUP LIMITED (GB) 2019-08-15 US disclosed
US-10273261-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags QUANTUMDX GROUP LIMITED (GB) 2019-04-30 US disclosed
US-20190004055-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS QUANTUMDX GROUP LIMITED (GB) 2019-01-03 US disclosed
EP-3400444-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS QuantuMDx Group Limited (GB) 2018-11-14 EP disclosed
WO-2017120148-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS QUANTUMDX GROUP LIMITED (GB) 2017-07-13 WO disclosed
US-20160139133-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS QUANTUMDX GROUP LIMITED (GB) 2016-05-19 US disclosed
EP-2241551-A1 METHOD FOR PRODUCING CYCLOPROPANE CARBOXYLIC ACID COMPOUND AND INTERMEDIATE THEREFOR Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
US-20070249822-A1 Photolabile Coumarinylmethyl Esters of Cyclic Nucleotides, Methods for their Preparation and Their Use FORSCHUNGSVERBUND BERLIN E.V. (DE) 2007-10-25 US disclosed
US-7138538-B2 Process for the separation of enantiomers and enantiopure reagent SOLVAY (SOCIETE ANONYME) (BE) 2006-11-21 US disclosed
EP-1276749-B1 PHOTO-LABILE COUMARINYLMETHYL ESTERS OF CYCLIC NUCLEOTIDES, METHOD FOR THE PRODUCTION AND USE THEREOF FORSCHUNGSVERBUND BERLIN EV (DE) 2005-08-24 EP disclosed
US-20040210060-A1 Process for the separation of enantiomers and enantiopure reagent SOLVAY S.A. (BE) 2004-10-21 US disclosed
US-6743373-B1 REAGENT BASED ON ENANTIOPURE AMINO ACID IN WHICH AMINO GROUP CARRIES ACTIVATING GROUP TO FORM ACTIVE PRECURSOR OF ISOCYANATE GROUP AND CARBOXYL GROUP IS SUBSTITUTED; SEPARATION OF ENANTIOMERS HAVING FREE FUNCTIONAL GROUP SOLVAY (SOCIETE ANONYME) (BE) 2004-06-01 US disclosed
EP-1276749-A1 NOVEL, PHOTO-LABILE CUMARINYLMETHYL ESTERS OF CYCLIC NUCLEOTIDES, METHOD FOR THE PRODUCTION AND USE THEREOF Forschungsverbund Berlin e.V. (DE) 2003-01-22 EP disclosed
WO-2001081360-A1 NOVEL, PHOTO-LABILE CUMARINYLMETHYL ESTERS OF CYCLIC NUCLEOTIDES, METHOD FOR THE PRODUCTION AND USE THEREOF FORSCHUNGSVERBUND BERLIN E.V. (DE) 2001-11-01 WO disclosed
EP-0853628-A1 PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE Forschungsverbund Berlin e.V. (DE) 1998-07-22 EP disclosed
WO-1997005155-A1 PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE FORSCHUNGSVERBUND BERLIN E.V. (DE) 1997-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10646416-B2 Microcapsules containing a gas-releasing photolabile compound and uses thereof ALOX5, TRPA1, FASN MEN1 2724/4885KMT2A 4780/4885CDC25B 151/4885
US-11180523-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags POLM, RNGTT, TYMP MEN1 2830/4885KMT2A 1303/4885CDC25B 1341/4885
US-20070249822-A1 Photolabile Coumarinylmethyl Esters of Cyclic Nucleotides, Methods for their Preparation and Their Use HCCS, NUDT1, CBR3 MEN1 2812/4885KMT2A 4838/4885CDC25B 272/4885
US-20190004055-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS POLM, RNGTT, TYMP MEN1 2830/4885KMT2A 1303/4885CDC25B 1341/4885
US-20040210060-A1 Process for the separation of enantiomers and enantiopure reagent DNPEP, DAO, ANPEP MEN1 3328/4885KMT2A 3108/4885CDC25B 2091/4885
US-10759824-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags POLM, RNGTT, TYMP MEN1 2830/4885KMT2A 1303/4885CDC25B 1341/4885
US-20190248827-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS POLM, RNGTT, TYMP MEN1 2830/4885KMT2A 1303/4885CDC25B 1341/4885
US-10273261-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags POLM, RNGTT, TYMP MEN1 2830/4885KMT2A 1303/4885CDC25B 1341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.