⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3602608 | 0.73 | REN (0.37) | — | |
| SCHEMBL9826702 | 0.71 | F2 (0.47) | — | |
| SCHEMBL3592113 | 0.69 | ALDH1A1 (0.42) | — | |
| SCHEMBL10129667 | 0.68 | PDE3B (0.50) | — | |
| SCHEMBL10129678 | 0.68 | PDE3B (0.50) | — | |
| SCHEMBL7472425 | 0.68 | PARP1 (0.45) | — | |
| SCHEMBL7470594 | 0.67 | USP2 (0.53) | — | |
| SCHEMBL3602609 | 0.67 | PDE3B (0.32) | — | |
| SCHEMBL7473281 | 0.67 | MEN1 (0.38) | — | |
| SCHEMBL7463472 | 0.67 | HSD17B10 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |