Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225479 | 0.89 | CA2 (0.58) | KMT2ACA2CAMK2AFFAR1AKR1B1 | |
| SCHEMBL21243832 | 0.87 | SRD5A2 (0.72) | SRD5A2NR3C1CA2CAMK2AFFAR1 | |
| SCHEMBL2999416 | 0.87 | SRD5A2 (0.72) | SRD5A2NR3C1CA2CAMK2AFFAR1 | |
| SCHEMBL18269514 | 0.85 | RAB9A (0.55) | PARP10KMT2ACA2CAMK2AFFAR1 | |
| SCHEMBL24677897 | 0.84 | FFAR1 (0.54) | SRD5A2PARP10PARP3NR3C1FFAR1 | |
| SCHEMBL31238525 | 0.84 | PARP10 (0.62) | PARP10PARP3KMT2ACA2LMNA | |
| SCHEMBL1125736 | 0.83 | ABCC4 (0.64) | KMT2ACA2CAMK2AFFAR1AKR1B1 | |
| SCHEMBL3962759 | 0.83 | FFAR1 (0.70) | SRD5A2PARP10PARP3FFAR1LMNA | |
| SCHEMBL1145770 | 0.81 | SRD5A2 (0.83) | SRD5A2NR3C1FFAR1AKR1B1LMNA | |
| SCHEMBL2353788 | 0.79 | CA2 (0.76) | SRD5A2PARP10KMT2ANR3C1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423434-A | Carbonamide derivative and preparation method thereof | 四川海思科制药有限公司 | 2020-07-17 | — | — | CN | disclosed |
| EP-2004185-B1 | NOVEL HETEROCYCLIC DIPHENYL ETHERS | BEXEL PHARMACEUTICALS INC (US) | 2013-06-26 | — | — | EP | disclosed |
| EP-2004185-B1 | NOVEL HETEROCYCLIC DIPHENYL ETHERS | BEXEL PHARMACEUTICALS INC (US) | 2013-06-26 | — | — | EP | disclosed |
| US-7781464-B2 | Heterocyclic diphenyl ethers | BEXEL PHARMACEUTICALS, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-7781464-B2 | Heterocyclic diphenyl ethers | BEXEL PHARMACEUTICALS, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-7781464-B2 | Heterocyclic diphenyl ethers | BEXEL PHARMACEUTICALS, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| WO-2007097992-A2 | NOVEL HETEROCYCLIC DIPHENYL ETHERS | BEXEL PHARMACEUTICALS, INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20060247285-A1 | Novel heterocyclic diphenyl ethers | BEXEL PHARMACEUTICALS, INC. | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247285-A1 | Novel heterocyclic diphenyl ethers | FFAR4, FFAR3, GPR119 | SRD5A2 336/4885PARP10 4372/4885PARP3 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.