Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30105737 | 0.98 | TSHR (0.55) | TSHRGPR35ALDH1A1TP53HPGD | |
| 1,2-Dichloroethane SCHEMBL28304825 | 0.96 | TSHR (0.53) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL17627174 | 0.85 | GPR35 (0.56) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL51277 | 0.85 | GPR35 (0.60) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL4231830 | 0.83 | ALDH1A1 (0.58) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL216753 | 0.83 | GPR35 (0.58) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL786832 | 0.81 | GAA (0.59) | TSHRGPR35ALDH1A1TP53HPGD | |
| Hydrochloric Acid SCHEMBL22773531 | 0.81 | GPR35 (0.56) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL131912 | 0.81 | GPR35 (0.56) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL786831 | 0.81 | ALDH1A1 (0.56) | TSHRGPR35ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594601-B | Method for preparing Saimiqili intermediate 2-methyl-4-aminophenol | 山东国邦药业有限公司 | 2023-02-28 | — | — | CN | claimed |
| CN-115594601-A | Method for preparing Saimiqili intermediate 2-methyl-4-aminophenol | 山东国邦药业有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115385880-A | Industrial preparation method of environment-friendly dronedarone key intermediate | 南京方生和医药科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-113354657-B | Mytoxin A prodrug and preparation method and application thereof | 国家纳米科学中心 | 2022-10-21 | — | — | CN | claimed |
| CN-113321698-B | Monomethyl auristatin E prodrug and preparation method and application thereof | 国家纳米科学中心 | 2022-08-23 | — | — | CN | claimed |
| CN-113321702-B | Monomethyl auristatin F methyl ester prodrug and preparation method and application thereof | 国家纳米科学中心 | 2022-08-05 | — | — | CN | claimed |
| CN-109651394-B | Benzoindolo [2,1-b ] [1,3] oxazine derivative cyanide ion probe and application thereof | 山东第一医科大学(山东省医学科学院) | 2021-07-20 | — | — | CN | claimed |
| CN-109970693-A | A kind of preparation method of dronedarone key intermediate | 南京方生和医药科技有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-105936626-A | Preparation method of amino protection group | 济南大学 | 2016-09-14 | — | — | CN | claimed |
| EP-2718393-B1 | NEW PHOTOCHROMIC COMPOUNDS, METHOD OF PRODUCTION THEREOF AND INTERMEDIATE COMPOUNDS | KAUNAS UNIVERSITY OF TECHNOLOGY (LT) | 2015-08-05 | — | — | EP | claimed |
| CN-102659726-B | Method for synthesis of dronedarone | FUJIAN COSUNTER PHARMACEUTICAL CO LTD | 2014-11-19 | — | — | CN | claimed |
| EP-2718393-A1 | NEW PHOTOCHROMIC COMPOUNDS, METHOD OF PRODUCTION THEREOF AND INTERMEDIATE COMPOUNDS | Kauno Technologijos Universitetas (LT) | 2014-04-16 | — | — | EP | claimed |
| WO-2014035224-A1 | NEW PHOTOCHROMIC COMPOUNDS, METHOD OF PRODUCTION THEREOF AND INTERMEDIATE COMPOUNDS | Kauno technologijos universitetas (LT) | 2014-03-06 | — | — | WO | claimed |
| CN-102659726-A | Method for synthesis of dronedarone | FUJIAN GUANGSHENGTANG PHARMACEUTICAL CO LTD | 2012-09-12 | — | — | CN | claimed |
| EP-0180785-A1 | Pharmaceutical preparation containing a combination of Nitrendipin and Enalapril and process for its preparation | BAYER AG (DE) | 1986-05-14 | — | — | EP | claimed |
| US-20250257069-A1 | JAK INHIBITOR ANALOGS, FORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2025-08-14 | — | — | US | disclosed |
| US-12378199-B2 | Rigidified pentadentate chelating agents useful for the [Al18F]2+ labelling of biomolecules | UNIVERSITÀ DEGLI STUDI DEL PIEMONTE ORIENTALE “A. AVOGADRO” (IT) | 2025-08-05 | — | — | US | disclosed |
| US-4122256-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4052433-A | INTERMEDIATES FOR BENZOFURANS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |
| US-3994879-A | CONDENSING AZOMETHINES, OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257069-A1 | JAK INHIBITOR ANALOGS, FORMULATIONS, AND USES THEREOF | JAK1, JAK3, JAK2 | TSHR 3612/4885GPR35 1683/4885ALDH1A1 2402/4885 |
| US-12378199-B2 | Rigidified pentadentate chelating agents useful for the [Al18F]2+ labelling of biomolecules | SLC29A1, APRT, SLC29A2 | TSHR 2022/4885GPR35 3482/4885ALDH1A1 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.