Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9501431 | 0.98 | GAA (0.58) | GAATHRBGPR35ALDH1A1TP53 | |
| SCHEMBL8709893 | 0.86 | THRB (0.56) | GAATHRBGPR35ALDH1A1TP53 | |
| SCHEMBL6691566 | 0.85 | GPR35 (0.56) | GAATHRBGPR35ALDH1A1TP53 | |
| SCHEMBL51277 | 0.85 | GPR35 (0.60) | GAATHRBGPR35ALDH1A1TP53 | |
| SCHEMBL4231830 | 0.83 | ALDH1A1 (0.58) | GAATHRBGPR35ALDH1A1TP53 | |
| SCHEMBL216753 | 0.83 | GPR35 (0.58) | GAATHRBGPR35ALDH1A1TP53 | |
| SCHEMBL2062221 | 0.82 | LOXL2 (0.55) | GAATHRBALDH1A1TSHRLOXL2 | |
| SCHEMBL8012475 | 0.82 | GAA (0.56) | GAATHRBGPR35ALDH1A1TP53 | |
| SCHEMBL786831 | 0.81 | ALDH1A1 (0.56) | GAATHRBGPR35ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL22773531 | 0.81 | GPR35 (0.56) | GAATHRBGPR35ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020230136-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |
| EP-2438068-B1 | SUBSTITUTED 6-(2-HYDROXYBENZYLAMINO)PURINE DERIVATIVES, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2017-03-01 | — | — | EP | disclosed |
| US-8492391-B2 | Substituted 6-(2-hydroxybenzylamino)purine derivatives, their use as medicaments and compositions containing these derivatives | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2013-07-23 | — | — | US | disclosed |
| US-20120070512-A1 | Substituted 6-(2-hydroxybenzylamino)purine Derivatives, Their Use as Medicaments and Compositions Containing These Derivatives | BIOPATTERNS, S.R.O (CZ) | 2012-03-22 | — | — | US | disclosed |
| EP-0946561-B1 | TRIAZOLO(4,5-D)PYRIMIDINYL DERIVATIVES AND THEIR USE AS MEDICAMENTS | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| US-6297232-B1 | TREATMENT OF PLATELET AGGREGATION DISORDERS. | ASTRAZENECA AB (SE) | 2001-10-02 | — | — | US | disclosed |
| EP-0946561-A1 | TRIAZOLO(4,5-D)PYRIMIDINYL DERIVATIVES AND THEIR USE AS MEDICAMENTS | Astra Pharmaceuticals Limited (GB) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028300-A1 | TRIAZOLO[4,5-D]PYRIMIDINYL DERIVATIVES AND THEIR USE AS MEDICAMENTS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-07-02 | — | — | WO | disclosed |
| EP-0226072-B1 | OXIDATION DYE CONTAINING 4-AMINO-2-AMINOMETHYL PHENOL | Wella Aktiengesellschaft (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4797130-A | DYE DEVELOPERS GOOD FOR RED COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| EP-0226072-A1 | Oxidation dye containing 4-amino-2-aminomethyl phenol | Wella Aktiengesellschaft (DE) | 1987-06-24 | — | — | EP | disclosed |
| WO-1987003475-A2 | OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS | WELLA AKTIENGESELLSCHAFT (DE) | 1987-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070512-A1 | Substituted 6-(2-hydroxybenzylamino)purine Derivatives, Their Use as Medicaments and Compositions Containing These Derivatives | CDK6, CCNI, CDK2 | GAA 2154/4885THRB 4433/4885GPR35 1867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.