Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3601453 | 0.99 | ALDH1A1 (0.42) | ALDH1A1BTKWNT1GSK3BDYRK1A | |
| SCHEMBL3606877 | 0.88 | ALDH1A1 (0.47) | ALDH1A1WNT1GSK3BDYRK1AF2 | |
| Hydrochloric Acid SCHEMBL3611595 | 0.87 | ALDH1A1 (0.46) | ALDH1A1WNT1GSK3BDYRK1AF2 | |
| SCHEMBL3608825 | 0.86 | SCD5 (0.53) | ALDH1A1ASIC3MAPTROCK2MEN1 | |
| SCHEMBL13504910 | 0.83 | SLC2A1 (0.48) | ALDH1A1WNT1GSK3BDYRK1AF2 | |
| Hydrochloric Acid SCHEMBL3604615 | 0.83 | SMN1; SMN2 (0.49) | ALDH1A1WNT1GSK3BDYRK1AF2 | |
| Hydrochloric Acid SCHEMBL3600084 | 0.82 | SLC2A1 (0.50) | ALDH1A1WNT1GSK3BDYRK1AF2 | |
| SCHEMBL3601422 | 0.82 | RAF1 (0.43) | ALDH1A1RAB9AGAAMAPTMAPK1 | |
| SCHEMBL3605849 | 0.81 | NAMPT (0.49) | WNT1GSK3BDYRK1AF2PLG | |
| SCHEMBL13504959 | 0.78 | SCD5 (0.52) | WNT1GSK3BDYRK1ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | ALDH1A1 430/4885BTK 1606/4885WNT1 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.