Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.64 |
| ▸ | RAB9A | P51151 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.62 |
| ▸ | PDE5A | O76074 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604259 | 0.88 | RAB9A (0.70) | NPC1RAB9AKMT2AMEN1ROCK1 | |
| SCHEMBL3594519 | 0.85 | ALDH1A1 (0.59) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3602966 | 0.80 | RAB9A (0.71) | NPC1RAB9AKMT2AMEN1ROCK1 | |
| SCHEMBL3606983 | 0.78 | KDM4E (0.57) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3601891 | 0.76 | GCK (0.57) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13357590 | 0.76 | ROCK1 (1.00) | NPC1RAB9AKMT2AMEN1ROCK1 | |
| SCHEMBL2187200 | 0.75 | CSNK1E (0.62) | NPC1RAB9AKMT2AMEN1ROCK1 | |
| SCHEMBL3602381 | 0.75 | PDE5A (0.62) | NPC1RAB9AKMT2AMEN1PDE5A | |
| SCHEMBL3599267 | 0.75 | GCK (0.54) | NPC1RAB9AKMT2AMEN1PDE5A | |
| SCHEMBL3610516 | 0.74 | ALDH1A1 (0.59) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | AADAC, HDHD5, HRH4 | NPC1 2323/4885RAB9A 2239/4885KMT2A 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.