Sugi Predict

Sugi Predict / Compounds / SCHEMBL3603564

SCHEMBL3603564

SCHEMBL3603564

COC(=O)CCCCC(CCc1ccccc1OCc1ccc(C2CCCCC2)cc1)[S+]([O-])c1ccc(C(=O)OC)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ MAPT P10636 3/20 0.35
▸ LMNA P02545 2/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ PTGER1 P34995 1/20 0.35
▸ PTGER4 P35408 1/20 0.35
▸ PTGER3 P43115 1/20 0.35
▸ PTGER2 P43116 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.34
▸ NPC1L1 Q9UHC9 1/20 0.33
▸ MGLL Q99685 1/20 0.33
▸ STAT3 P40763 1/20 0.33
▸ FFAR4 Q5NUL3 1/20 0.33
▸ CSF1R P07333 1/20 0.33
▸ HRH3 Q9Y5N1 1/20 0.33
▸ PRMT5 O14744 1/20 0.32
▸ EGFR P00533 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13443519 0.86 PTGER1 (0.45) HPGDPTGER1PTGER4PTGER3PTGER2
SCHEMBL3598271 0.84 PDE4A (0.39) KMT2ATP53HPGDMAPTLMNA
SCHEMBL3602387 0.84 MAPT (0.37) KMT2ATP53HPGDMAPTLMNA
SCHEMBL3600414 0.84 RAB9A (0.37) KMT2ATP53HPGDMAPTLMNA
SCHEMBL3604761 0.84 MAPT (0.36) KMT2ATP53HPGDMAPTLMNA
SCHEMBL13443165 0.82 PTGFR (0.40) PTGER1PTGER4PTGER3PTGER2FFAR4
SCHEMBL3591301 0.81 PTGER1 (0.37) KMT2APTGER1PTGER4PTGER3PTGER2
SCHEMBL13009721 0.79 BCHE (0.38) KMT2ATP53HPGDMAPTLMNA
SCHEMBL3601624 0.78 POLB (0.42) KMT2APTGER1PTGER4PTGER3PTGER2
SCHEMBL13443292 0.75 MEN1 (0.38) KMT2AHPGDMAPTLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7674825-B2 Dicarboxylic acid derivatives with pharmaceutical properties BAYER AKTIENGESELLSCHAFT (DE) 2010-03-09 — — US disclosed
US-7674825-B2 Dicarboxylic acid derivatives with pharmaceutical properties BAYER AKTIENGESELLSCHAFT (DE) 2010-03-09 — — US disclosed
US-7674825-B2 Dicarboxylic acid derivatives with pharmaceutical properties BAYER AKTIENGESELLSCHAFT (DE) 2010-03-09 — — US disclosed
US-20080058314-A1 Novel dicarboxylic acid derivatives with pharmaceutical properties BAYER AKTIENGESELLSCHAFT 2008-03-06 — — US disclosed
US-20080058314-A1 Novel dicarboxylic acid derivatives with pharmaceutical properties BAYER AKTIENGESELLSCHAFT 2008-03-06 — — US disclosed
US-20080058314-A1 Novel dicarboxylic acid derivatives with pharmaceutical properties BAYER AKTIENGESELLSCHAFT 2008-03-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080058314-A1 Novel dicarboxylic acid derivatives with pharmaceutical properties PC, GOT2, SDHA KMT2A 3707/4885TP53 3656/4885HPGD 394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.