Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.65 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.65 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19219074 | 0.95 | CYP17A1 (0.69) | CYP17A1CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL9103132 | 0.85 | CYP17A1 (0.53) | CYP17A1CYP11B1CYP11B2CYP3A4CYP2C9 | |
| Pyridine SCHEMBL30984530 | 0.84 | CYP3A4 (0.70) | CYP17A1CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL1464252 | 0.84 | — | — | |
| SCHEMBL338810 | 0.84 | LTA4H (0.70) | CYP17A1CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL18770350 | 0.82 | CYP17A1 (1.00) | CYP17A1CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL7455134 | 0.81 | LTA4H (0.67) | CYP17A1CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL27709556 | 0.81 | CYP3A4 (0.60) | CYP17A1CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL29590048 | 0.79 | CYP2A6 (1.00) | CYP17A1CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL158705 | 0.79 | CYP2A6 (1.00) | CYP17A1CYP11B1CYP11B2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9241522-A | — | — | None | — | — | JP | disclosed |
| JP-9241522-A | — | — | None | — | — | JP | disclosed |
| CN-119409858-A | Protonated product of pyridine derivative and compound, preparation method and application thereof | 天津师范大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-118290753-A | Sulfamic acid-loaded aluminum-based metal organic framework material, preparation method and application thereof | 南京理工大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-117700457-A | Electrochromic compound, preparation method and application | 北京大学深圳研究生院 | 2024-03-15 | — | — | CN | disclosed |
| CN-117383993-A | Direct cross coupling method of aryl thiophenol and aryl bromide | 南京工业大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-115135659-A | Morpholine derivatives and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2022152229-A1 | CLASS OF MORPHOLINE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-07-21 | — | — | WO | disclosed |
| CN-111902188-A | Treatment of demyelinating diseases | 马特恩制药股份公司 | 2020-11-06 | — | — | CN | disclosed |
| WO-2019000024-A1 | HIGHLY EMISSIVE PYRIDINIUM ENOLATES | THE UNIVERSITY OF MELBOURNE (AU) | 2019-01-03 | — | — | WO | disclosed |
| US-5665739-A | CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-09 | — | — | US | disclosed |
| EP-0602523-B1 | Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, as well as a medicament containing them | HOECHST AG (DE) | 1996-12-11 | — | — | EP | disclosed |
| US-5556524-A | DIAGNOSTICS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 1996-09-17 | — | — | US | disclosed |
| EP-0668277-A1 | Bipyridyl-oligothiophene derivatives as electron-conducting materials | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 1995-08-23 | — | — | EP | disclosed |
| EP-0602523-A1 | Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, as well as a medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4870087-A | Indole containing, 2-thienyl-1,2,3,6-tetrahydropyridyls and their pharmaceutical use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-26 | — | — | US | disclosed |
| EP-0121716-B1 | INDOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 1987-12-09 | — | — | EP | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |
| EP-0121716-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1984-10-17 | — | — | EP | disclosed |