Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | BRD4 | O60885 | 5/20 | 0.53 |
| ▸ | BRD2 | P25440 | 2/20 | 0.53 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.53 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.53 |
| ▸ | PDE4A | P27815 | 5/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005448 | 0.74 | MAPK1 (0.70) | MEN1KMT2AALDH1A1BRD4BRD2 | |
| SCHEMBL10813831 | 0.71 | PDE4A (0.83) | MEN1KMT2AALDH1A1BRD4BRD2 | |
| SCHEMBL7457891 | 0.70 | MEN1 (1.00) | MEN1KMT2AALDH1A1BRD4BRD2 | |
| SCHEMBL19066317 | 0.69 | BRD4 (1.00) | MEN1KMT2AALDH1A1BRD4BRD2 | |
| SCHEMBL3177931 | 0.69 | ADORA2A (0.42) | MEN1KMT2AALDH1A1BRD4BRD2 | |
| SCHEMBL11399596 | 0.69 | MEN1 (0.95) | MEN1KMT2AALDH1A1BRD4BRD2 | |
| SCHEMBL11458744 | 0.68 | MEN1 (0.74) | MEN1KMT2AALDH1A1BRD4BRD2 | |
| SCHEMBL3104007 | 0.67 | MEN1 (0.75) | MEN1KMT2AALDH1A1BRD4BRD2 | |
| SCHEMBL3902928 | 0.67 | PDE4A (1.00) | MEN1KMT2AALDH1A1BRD4BRD2 | |
| SCHEMBL515898 | 0.67 | PDE4A (0.69) | MEN1KMT2AALDH1A1BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160354-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160354-A1 | NOVEL COMPOUNDS | HCAR1, XDH, GPR84 | MEN1 3009/4885KMT2A 3023/4885ALDH1A1 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.