Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 2/20 | 0.62 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | BCR | P11274 | 1/20 | 0.59 |
| ▸ | PRKCA | P17252 | 1/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.59 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 4/20 | 0.55 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469256 | 0.87 | CDK1 (0.61) | ABL1PRKCAPRKCDCAMK2DCDK2 | |
| SCHEMBL7462357 | 0.86 | CDK1 (0.65) | EIF2AK2ABL1BCRPIK3CAPIK3CB | |
| SCHEMBL3246773 | 0.81 | NUDT1 (0.61) | EIF2AK2ABL1BCRPRKCAPRKCD | |
| SCHEMBL3246795 | 0.81 | NUDT1 (0.62) | EIF2AK2ABL1BCRPRKCAPRKCD | |
| SCHEMBL3602654 | 0.80 | ABL1 (0.59) | EIF2AK2ABL1BCRPRKCAPRKCD | |
| SCHEMBL3600200 | 0.80 | CDK2 (0.64) | EIF2AK2ABL1BCRPRKCAPRKCD | |
| SCHEMBL3605872 | 0.80 | PIK3CA (0.62) | EIF2AK2ABL1BCRPRKCAPRKCD | |
| SCHEMBL3247335 | 0.80 | EIF2AK2 (0.62) | EIF2AK2ABL1BCRPRKCAPRKCD | |
| SCHEMBL3251717 | 0.80 | CDK1 (0.76) | EIF2AK2ABL1BCRPRKCAPRKCD | |
| SCHEMBL3599515 | 0.80 | ABL1 (0.65) | EIF2AK2ABL1BCRPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048597-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
| US-20100048597-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
| US-20100048597-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048597-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | FADS1 1051/4885EIF2AK2 2174/4885ABL1 3215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.