Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2106669 | 0.99 | SMN1; SMN2 (0.63) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1810665 | 0.90 | MEN1 (0.81) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2103872 | 0.88 | MEN1 (0.78) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2106666 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3610429 | 0.85 | ALDH1A1 (0.65) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL30739691 | 0.84 | KMT2A (0.68) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2104842 | 0.82 | MEN1 (0.60) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2058337 | 0.81 | ALDH1A1 (0.71) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6812233 | 0.81 | MEN1 (0.67) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2105822 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046765-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-10-17 | — | — | EP | disclosed |
| US-20100048652-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2046765-A1 | INSECTICIDAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012027-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048652-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | SMN1; SMN2 556/4885MEN1 677/4885KMT2A 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.