Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818135 | 0.90 | ALDH1A1 (0.80) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL3606020 | 0.85 | SMN1; SMN2 (0.65) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2263282 | 0.84 | RAB9A (0.71) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2106666 | 0.83 | SMN1; SMN2 (0.59) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL2106669 | 0.83 | SMN1; SMN2 (0.63) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6819638 | 0.83 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3592038 | 0.81 | RAB9A (0.78) | ALDH1A1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL1810078 | 0.81 | RAB9A (0.59) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL1813249 | 0.80 | RAB9A (0.81) | ALDH1A1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL6242208 | 0.79 | RAB9A (0.84) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046765-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-10-17 | — | — | EP | disclosed |
| US-20100048652-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2046765-A1 | INSECTICIDAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012027-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048652-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | ALDH1A1 251/4885L3MBTL1 419/4885RAB9A 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.