SCHEMBL2058337

SCHEMBL2058337

O=C(O)c1cccc(NC(=O)c2ccccc2C(=O)O)c1

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.71
MEN1 O00255 5/20 0.69
KMT2A Q03164 5/20 0.69
HTT P42858 2/20 0.64
SMN1; SMN2 Q16637 3/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
KCNK3 O14649 3/20 0.61
KCNK9 Q9NPC2 3/20 0.61
CYP1A2 P05177 1/20 0.60
HPSE Q9Y251 1/20 0.60
NR1H4 Q96RI1 1/20 0.60
PPARA Q07869 1/20 0.58
GPR35 Q9HC97 1/20 0.58
LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12700378 0.90 ALDH1A1 (0.70) ALDH1A1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL11864904 0.90 ALDH1A1 (0.67) ALDH1A1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL13927138 0.90 ALDH1A1 (0.81) ALDH1A1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL18132551 0.89 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL29204765 0.89 HPSE (0.63) ALDH1A1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL9161426 0.88 MEN1 (0.66) ALDH1A1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL9164792 0.88 MEN1 (0.66) ALDH1A1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL17538449 0.86 KMT2A (0.65) ALDH1A1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL6852858 0.86 MEN1 (0.60) ALDH1A1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL17538597 0.86 KMT2A (0.65) ALDH1A1MEN1KMT2AHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2115111-B1 BENZOPHENONE OR BENZOIC ACID ANILIDE DERIVATIVES CONTAINING CARBOXYL GROUPS AS ENZYME STABILIZERS HENKEL AG & CO KGAA (DE) 2014-04-30 EP claimed
US-7968508-B2 Benzophenone or benzoic acid anilide derivatives containing carboxyl groups as enzyme stabilizers HENKEL AG & CO. KGAA (DE) 2011-06-28 US claimed
US-20100062964-A1 Benzophenone or Benzoic Acid Anilide Derivatives containing Carboxyl Groups as Enzyme Stabilizers HENKEL AG & CO., KGAA (DE) 2010-03-11 US claimed
US-12310944-B2 Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and use thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2025-05-27 US disclosed
US-20230165833-A1 Selective Butyrylcholinesterase Inhibitor or Pharmaceutically Acceptable Salt Thereof, Preparation Method and Use Thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2023-06-01 US disclosed
WO-2021042410-A1 SELECTIVE BUTYRYLCHOLINESTERASE INHIBITOR OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 中国药科大学 2021-03-11 WO disclosed
CN-110627767-B Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and application thereof 中国药科大学 2020-08-25 CN disclosed
CN-110627767-A Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and application thereof 中国药科大学 2019-12-31 CN disclosed
US-10166237-B2 Compounds and methods for inducing chondrogenesis THE SCRIPPS RESEARCH INSTITUTE (US) 2019-01-01 US disclosed
US-20170112843-A1 COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS THE SCRIPPS RESEARCH INSTITUTE 2017-04-27 US disclosed
US-9464065-B2 Compounds and methods for inducing chondrogenesis THE SCRIPPS RESEARCH INSTITUTE (US) 2016-10-11 US disclosed
US-7968508-B2 Benzophenone or benzoic acid anilide derivatives containing carboxyl groups as enzyme stabilizers HENKEL AG & CO. KGAA (DE) 2011-06-28 US disclosed
US-7968508-B2 Benzophenone or benzoic acid anilide derivatives containing carboxyl groups as enzyme stabilizers HENKEL AG & CO. KGAA (DE) 2011-06-28 US disclosed
WO-2011026107-A1 PHTHALANILATE COMPOUNDS AND METHODS OF USE UNIVERSITY OF NOTRE DAME DU LAC (US) 2011-03-03 WO disclosed
US-20100062964-A1 Benzophenone or Benzoic Acid Anilide Derivatives containing Carboxyl Groups as Enzyme Stabilizers HENKEL AG & CO., KGAA (DE) 2010-03-11 US disclosed
US-20100062964-A1 Benzophenone or Benzoic Acid Anilide Derivatives containing Carboxyl Groups as Enzyme Stabilizers HENKEL AG & CO., KGAA (DE) 2010-03-11 US disclosed
US-20100062964-A1 Benzophenone or Benzoic Acid Anilide Derivatives containing Carboxyl Groups as Enzyme Stabilizers HENKEL AG & CO., KGAA (DE) 2010-03-11 US disclosed
EP-2115111-A1 BENZOPHENONE OR BENZOIC ACID ANILIDE DERIVATIVES CONTAINING CARBOXYL GROUPS AS ENZYME STABILIZERS Henkel AG & Co. KGaA (DE) 2009-11-11 EP disclosed
WO-2008107030-A1 BENZOPHENONE OR BENZOIC ACID ANILIDE DERIVATIVES CONTAINING CARBOXYL GROUPS AS ENZYME STABILIZERS HENKEL AG & CO. KGAA (DE) 2008-09-12 WO disclosed
US-3935015-A Silver halide color photographic materials containing 3-anilino-5-pyrazolane couplers FUJI PHOTO FILM CO., LTD. (JA) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10166237-B2 Compounds and methods for inducing chondrogenesis COL2A1, BMP4, BMP2 ALDH1A1 63/4885MEN1 4660/4885KMT2A 3000/4885
US-20230165833-A1 Selective Butyrylcholinesterase Inhibitor or Pharmaceutically Acceptable Salt Thereof, Preparation Method and Use Thereof BCHE, ACHE, BACE1 ALDH1A1 378/4885MEN1 2484/4885KMT2A 2073/4885
US-20170112843-A1 COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS COL2A1, BMP4, BMP2 ALDH1A1 63/4885MEN1 4660/4885KMT2A 3000/4885
US-12310944-B2 Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and use thereof BCHE, ACHE, BACE1 ALDH1A1 399/4885MEN1 2495/4885KMT2A 2226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.