Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | HTR1D | P28221 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR1B | P28222 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR5A | P47898 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5619271 | 0.88 | PRKCI (0.38) | MEN1KMT2AHSD17B10PARP1CCNC | |
| SCHEMBL5618594 | 0.87 | PARP1 (0.38) | MEN1TSHRKMT2AHSD17B10PARP1 | |
| Hydrochloric Acid SCHEMBL10630450 | 0.85 | PARP1 (0.37) | MEN1TSHRKMT2AHSD17B10PARP1 | |
| Bromide SCHEMBL9317974 | 0.85 | PARP1 (0.37) | MEN1TSHRKMT2AHSD17B10PARP1 | |
| SCHEMBL1018547 | 0.83 | PARP1 (0.42) | MEN1TSHRKMT2AHSD17B10PARP1 | |
| SCHEMBL2399438 | 0.82 | MEN1 (0.43) | MEN1TSHRKMT2ALMNAADRA2A | |
| SCHEMBL30824614 | 0.77 | DGAT1 (0.41) | BACE1HMGB1TAAR1HTR1AHTR1D | |
| SCHEMBL28252973 | 0.77 | DGAT1 (0.41) | BACE1HMGB1TAAR1HTR1AHTR1D | |
| SCHEMBL4155497 | 0.77 | PKM (0.36) | MEN1CYP1A2TSHRKMT2AHSD17B10 | |
| SCHEMBL59737 | 0.77 | NNMT (0.36) | MEN1TSHRKMT2AHSD17B10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723331-B2 | Thienopyrimidine compounds and uses thereof | ASTRAZENECA AB (SE) | 2010-05-25 | — | — | US | disclosed |
| US-20080051405-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051405-A1 | Therapeutic Agents | GPR119, HTT, IAPP | BACE1 30/4885HMGB1 1197/4885TAAR1 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.