Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.51 |
| ▸ | PRKCA | P17252 | 4/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | LCK | P06239 | 2/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | PRKCB | P05771 | 1/20 | 0.51 |
| ▸ | PRKCH | P24723 | 1/20 | 0.51 |
| ▸ | PRKCI | P41743 | 1/20 | 0.51 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.51 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.51 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.50 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.49 |
| ▸ | BCR | P11274 | 5/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13503014 | 0.90 | PIK3C3 (0.53) | ABL1PRKCAPRKCDEGFRLCK | |
| SCHEMBL3609139 | 0.82 | PIK3CG (0.55) | ABL1PRKCAPRKCDEGFRLCK | |
| SCHEMBL3613255 | 0.81 | TEK (0.51) | LCKDYRK1AAURKAKDRAURKB | |
| SCHEMBL3607411 | 0.80 | GSK3B (0.59) | ABL1LCKACVR1GSK3BCDK4 | |
| SCHEMBL3603447 | 0.80 | ABL1 (0.48) | ABL1PRKCAPRKCDEGFRLCK | |
| SCHEMBL3596098 | 0.79 | CDK9 (0.76) | ABL1LCKACVR1GSK3BCDK4 | |
| SCHEMBL3614099 | 0.79 | ABL1 (0.63) | ABL1PRKCAPRKCDLCKPRKD3 | |
| SCHEMBL3598695 | 0.79 | JAK2 (0.56) | ABL1PRKCAPRKCDEGFRLCK | |
| SCHEMBL3617309 | 0.79 | PIK3CA (0.64) | ABL1PRKCAEGFRPRKD3ACVR1 | |
| SCHEMBL3616129 | 0.79 | ABL1 (0.56) | ABL1PRKCALCKBCRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048597-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
| US-20100048597-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
| US-20100048597-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
| WO-2008079933-A2 | HETEROARYL-HETEROARYL COMPOUNDS AS CDK INHIBITORS FOR THE TREATMENT OF CANCER, INFLAMMATION AND VIRAL INFECTIONS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048597-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | ABL1 3215/4885PRKCA 4612/4885PRKCD 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.