SCHEMBL3608312

SCHEMBL3608312

Cn1ncc(-c2c[c]ccc2)n1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM3 P20309 1/20 0.35
AOC3 Q16853 2/20 0.35
BRD4 O60885 1/20 0.31
BRD3 Q15059 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1033250 0.78 AOC3 (0.40) KMT2ACHRM2CHRM3AOC3BRD4
SCHEMBL62501 0.77 KMT2A (0.62) KMT2A
SCHEMBL368047 0.70 DYRK1A (0.43) BRD4
SCHEMBL2658449 0.69 IDO1 (0.47) KMT2A
SCHEMBL1823663 0.69 PPARA (0.40)
SCHEMBL29277768 0.69 BRD4 (0.36) KMT2ABRD4
SCHEMBL30212958 0.69 METAP2 (0.47) KMT2ABRD4
SCHEMBL5610082 0.69 CYP2E1 (0.54) KMT2A
SCHEMBL610112 0.67 ALDH1A1 (0.33)
SCHEMBL5048013 0.67 AOC3 (0.43) CHRM2CHRM3AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170303629-A1 Non-Toxin Adhesiveless Slipper and Processing Method Thereof ZHANG ZILIANG (CN) 2017-10-26 US disclosed
US-20130045353-A1 Chemical Resistant Membrane INDUSTRIAL TEXTILES & PLASTICS LTD. (GB) 2013-02-21 US disclosed
EP-2489509-A1 Chemical Resistant Membrane Industrial Textiles & Plastics Limited (GB) 2012-08-22 EP disclosed
US-7745680-B1 Compositions, methods, and systems for reducing contamination STREAMLINE INNOVATIONS, INC. 2010-06-29 US disclosed
CN-101421234-A Is suitable for treating p-hydroxytryptamine 5HT6Heterocyclic aryl sulfones of receptor-modulated responsive disorders ABBOTT GMBH (DE) 2009-04-29 CN disclosed
CN-101421264-A Is suitable for treating serotonin 5HT6Heterocyclic compounds for receptor-modulated responsive disorders ABBOTT GMBH & CO KG (DE) 2009-04-29 CN disclosed
EP-2029528-A1 HETEROCYCLIC ARYLSULPHONES SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5HT6 RECEPTOR Abbott GmbH & Co. KG (DE) 2009-03-04 EP disclosed
WO-2007118899-A1 HETEROCYCLIC ARYLSULPHONES SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5HT6 RECEPTOR ABBOTT GMBH & CO. KG (DE) 2007-10-25 WO disclosed