Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 6/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SULT1A1 | P50225 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360263 | 0.84 | RAB9A (0.55) | HTTGAAAPPMAPTSMN1; SMN2 | |
| SCHEMBL12505621 | 0.83 | RAB9A (0.38) | HTTGAAL3MBTL1APPCA12 | |
| SCHEMBL360852 | 0.80 | MAPT (0.58) | HTTAPPCA12CA1CA2 | |
| SCHEMBL371310 | 0.74 | CA1 (0.42) | HTTGAACA12CA1CA2 | |
| SCHEMBL360416 | 0.71 | CA2 (0.41) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL31298 | 0.71 | HTT (1.00) | HTTGAAL3MBTL1APPCA12 | |
| Hydrochloric Acid SCHEMBL11729261 | 0.70 | HTT (0.96) | HTTGAAL3MBTL1APPCA12 | |
| SCHEMBL2090640 | 0.68 | AR (0.67) | HTTGAAL3MBTL1ARMAPT | |
| SCHEMBL2217147 | 0.67 | HTT (0.66) | HTTGAAL3MBTL1ARAPP | |
| SCHEMBL13279558 | 0.67 | AR (0.70) | HTTGAAL3MBTL1ARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |