Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | APP | P05067 | 4/20 | 0.48 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505621 | 0.84 | RAB9A (0.38) | RAB9ANPC1MAPTHTTALDH1A1 | |
| SCHEMBL359189 | 0.84 | HTT (0.54) | RAB9ANPC1MAPTHTTALDH1A1 | |
| SCHEMBL360852 | 0.81 | MAPT (0.58) | RAB9ANPC1MAPTHTTSMN1; SMN2 | |
| SCHEMBL359742 | 0.76 | GAA (0.41) | RAB9ANPC1MAPTHTTALDH1A1 | |
| SCHEMBL371310 | 0.75 | CA1 (0.42) | RAB9ANPC1MAPTHTTALDH1A1 | |
| SCHEMBL360416 | 0.72 | CA2 (0.41) | RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL105971 | 0.72 | RAB9A (0.61) | RAB9ANPC1MAPTHTTALDH1A1 | |
| SCHEMBL1530370 | 0.71 | MAPT (0.64) | RAB9ANPC1MAPTHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10643734 | 0.71 | RAB9A (0.59) | RAB9ANPC1MAPTHTTALDH1A1 | |
| SCHEMBL2098849 | 0.69 | RAB9A (0.56) | RAB9ANPC1MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |