Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.42 |
| ▸ | CA2 | P00918 | 12/20 | 0.42 |
| ▸ | CA9 | Q16790 | 12/20 | 0.42 |
| ▸ | CA12 | O43570 | 11/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360416 | 0.78 | CA2 (0.41) | CA1CA2CA9CA12NPC1 | |
| SCHEMBL360263 | 0.75 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL359189 | 0.74 | HTT (0.54) | CA1CA2CA9CA12NPC1 | |
| SCHEMBL12505621 | 0.74 | RAB9A (0.38) | CA1CA2CA9CA12NPC1 | |
| SCHEMBL360852 | 0.71 | MAPT (0.58) | CA1CA2CA9CA12NPC1 | |
| SCHEMBL359742 | 0.69 | GAA (0.41) | CA1CA2CA9CA12NPC1 | |
| SCHEMBL21802735 | 0.68 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL21395672 | 0.68 | AXL (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1AXL | |
| SCHEMBL248719 | 0.58 | ERN1 (0.50) | ALDH1A1 | |
| SCHEMBL29572092 | 0.58 | ALDH1A1 (0.38) | RAB9AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |