Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.34 |
| ▸ | FUT6 | P51993 | 1/20 | 0.34 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.34 |
| ▸ | ST3GAL1 | Q11201 | 1/20 | 0.34 |
| ▸ | ST3GAL3 | Q11203 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 5/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4230579 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL6111224 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL4241344 | 0.81 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3598687 | 0.78 | FFAR4 (0.40) | ERN1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL17535618 | 0.74 | EZH2 (0.32) | PRKDCALDH1A1SMN1; SMN2 | |
| SCHEMBL3606171 | 0.73 | ALDH1A1 (0.34) | ALDH1A1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL8887766 | 0.72 | IDO1 (0.32) | ST6GAL1FUT6FUT5ST3GAL1ST3GAL3 | |
| SCHEMBL5722906 | 0.72 | FFAR4 (0.42) | ERN1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8887535 | 0.71 | ST6GAL1 (0.36) | ST6GAL1FUT6FUT5ST3GAL1ST3GAL3 | |
| SCHEMBL273128 | 0.70 | LMNA (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553074-B1 | FUSED BENZENE DERIVATIVE AND USE | TAKEDA PHARMACEUTICAL (JP) | 2014-06-18 | — | — | EP | disclosed |
| US-7649001-B2 | Fused benzene derivative and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-19 | — | — | US | disclosed |
| US-20060106067-A1 | Fused benzene derivative and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1553074-A1 | FUSED BENZENE DERIVATIVE AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106067-A1 | Fused benzene derivative and use | AR, NR5A1, CBR3 | PIK3CD 4051/4885PIK3CA 3653/4885PIK3CB 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.