Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.46 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605553 | 0.85 | FFAR1 (0.52) | PPARAMAPTHIF1AFFAR1HDAC4 | |
| SCHEMBL3613056 | 0.84 | MEN1 (0.49) | PPARASMN1; SMN2GAAMAPTALOX15 | |
| SCHEMBL3247396 | 0.84 | FFAR1 (0.56) | PPARAMAPTFFAR1NPC1RAB9A | |
| SCHEMBL3591356 | 0.82 | HIF1A (0.59) | SMN1; SMN2GAAMAPTKDM4EHIF1A | |
| SCHEMBL3099350 | 0.82 | KCNQ3 (0.53) | PPARAKCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL20641771 | 0.81 | P4HTM (0.59) | P4HTMPPARAKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL18600165 | 0.77 | CYP1A2 (0.55) | P4HTMPPARAKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL19690469 | 0.75 | KCNQ3 (0.57) | P4HTMPPARAKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL3596698 | 0.74 | PPARA (0.55) | PPARAKCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL15348110 | 0.73 | KCNQ3 (0.56) | P4HTMPPARAKCNQ3KCNQ2KCNQ4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063044-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063044-A1 | SUBSTITUTED ANILINE DERIVATIVES | NDUFS3, NAT1, PRMT3 | P4HTM 3058/4885PPARA 3106/4885KCNQ3 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.