Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 2/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.46 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.46 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099035 | 0.91 | PPARA (0.51) | PPARAFFAR1ADRA2ACRHR1TRPA1 | |
| SCHEMBL3247396 | 0.90 | FFAR1 (0.56) | PPARAFFAR1CRHR1TRPA1PTGDR2 | |
| SCHEMBL3112934 | 0.83 | KCNQ2 (0.52) | PPARAFFAR1ADRA2ACRHR1TRPA1 | |
| SCHEMBL3094660 | 0.82 | RAB9A (0.49) | PPARAFFAR1ADRA2ACRHR1ALDH1A1 | |
| SCHEMBL30796155 | 0.81 | ADRA2A (0.48) | PPARAFFAR1ADRA2ACRHR1KCNQ3 | |
| SCHEMBL3112550 | 0.81 | FFAR1 (0.51) | PPARAFFAR1ADRA2ACRHR1PTGDR2 | |
| SCHEMBL30795257 | 0.79 | KCNQ2 (0.60) | PPARAFFAR1ADRA2ACRHR1KCNQ3 | |
| SCHEMBL3089700 | 0.79 | KCNQ2 (0.60) | PPARAFFAR1ADRA2ACRHR1KCNQ3 | |
| SCHEMBL3112562 | 0.79 | ADRA2A (0.51) | PPARAFFAR1ADRA2ACRHR1KCNQ3 | |
| SCHEMBL19690431 | 0.78 | FFAR1 (0.58) | PPARAFFAR1ADRA2ATRPA1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063044-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2010-03-11 | — | — | US | disclosed |
| CN-101056845-A | Substituted aniline derivatives | LUNDBECK & CO AS H (DK) | 2007-10-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063044-A1 | SUBSTITUTED ANILINE DERIVATIVES | NDUFS3, NAT1, PRMT3 | PPARA 3106/4885FFAR1 1653/4885ADRA2A 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.