Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22871669 | 0.83 | GPR119 (0.48) | GPR119PIK3CDPTPN2PTPN1PTPN6 | |
| SCHEMBL950789 | 0.80 | GPR119 (0.53) | GPR119PTPN2PTPN1PTPN6HPGD | |
| SCHEMBL7397405 | 0.77 | GPR119 (0.44) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL3623892 | 0.76 | GPR119 (0.45) | GPR119USP30 | |
| SCHEMBL2940507 | 0.74 | HPGD (0.50) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL20566340 | 0.74 | HPGD (0.50) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL5646218 | 0.74 | HPGD (0.50) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL4274742 | 0.74 | HPGD (0.50) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL12096407 | 0.74 | HPGD (0.50) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL4121106 | 0.74 | GPR119 (0.43) | GPR119PIK3CDPTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286181-A1 | PYRROLE DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286181-A1 | PYRROLE DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | PGLS, UROD, GMPS | GPR119 4408/4885PIK3CD 786/4885PTPN2 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.