Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL6757121 | 0.90 | KDM4E (0.47) | TPMTSGK1CAMKK2DCLRE1ADCLRE1B | |
| SCHEMBL16831460 | 0.84 | PTPRC (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29907920 | 0.83 | CA12 (0.47) | CYP1A2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8193407 | 0.83 | PPARA (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25342808 | 0.82 | PTPRC (0.42) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL18038517 | 0.82 | MAP2K2 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23486432 | 0.82 | SGK1 (0.44) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL3386626 | 0.81 | PPARA (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28795337 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1KMT2ASMN1; SMN2CA12 | |
| SCHEMBL5576093 | 0.79 | PTPRC (0.40) | GABRA1GABRB2PTPRCPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158340-A1 | PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SAME | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2024-05-16 | — | — | US | disclosed |
| WO-2022235875-A1 | PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SαAME | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2022-11-10 | — | — | WO | disclosed |
| EP-2655382-B1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2022-09-28 | — | — | EP | disclosed |
| CN-115052855-A | Preparation method of amide compound, crystal form and salt thereof | 昊运股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| EP-3368529-B1 | HETEROARYLCARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2022-04-06 | — | — | EP | disclosed |
| US-10750746-B2 | Structure, synthesis, and applications for poly (phenylene) ethynylenes (PPEs) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-10399961-B2 | Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-09-03 | — | — | US | disclosed |
| US-20190116797-A1 | STRUCTURE, SYNTHESIS, AND APPLICATIONS FOR POLY(PHENYLENE ETHYNYLENES) (PPEs) | UNIV FLORIDA (US) | 2019-04-25 | — | — | US | disclosed |
| US-10243151-B2 | Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2019-03-26 | — | — | US | disclosed |
| US-10174042-B2 | Structure, synthesis, and applications for poly (phenylene) ethynylenes (PPEs) | STC.UNM (US) | 2019-01-08 | — | — | US | disclosed |
| US-5202471-A | Skin disorders | ALLERGAN, INC. (US) | 1993-04-13 | — | — | US | disclosed |
| US-5162546-A | ACETYLENES DISUBSTITUTED WITH A PHENYL GROUP AND A 2-SUBSTITUTED CHROMANYL, THIOCHROMANYL OR 1,2,3,4-TETRAHYDROQUINOLINYL GROUP HAVING RETINOID-LIKE ACTIVITY | ALLERGAN, INC. (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1992006084-A1 | CHROMANS AND THIOCHROMANS WITH RETINOID-LIKE ACTIVITY | ALLERGAN, INC. (US) | 1992-04-16 | — | — | WO | disclosed |
| US-5053523-A | Chemical intermediate for compounds having retinoic acid-like activity | ALLERGAN, INC. (US) | 1991-10-01 | — | — | US | disclosed |
| US-5023341-A | Acetylene thiochroman | ALLERGAN, INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0419132-A2 | Process and intermediates for preparing compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity | ALLERGAN, INC. (US) | 1991-03-27 | — | — | EP | disclosed |
| EP-0419131-A2 | Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity | ALLERGAN, INC. (US) | 1991-03-27 | — | — | EP | disclosed |
| US-4980369-A | ANTIARTHRITIC AGENTS, SKIN DISORDERS, ANTIULCER AGENTS, WOUND HEALING AGENTS | ALLERGAN, INC. (US) | 1990-12-25 | — | — | US | disclosed |
| US-4017543-A | ANTIARRHYTHMIA | MERCK & CO., INC. (US) | 1977-04-12 | — | — | US | disclosed |
| US-3957871-A | ANTIARRHYTHMIA AGENTS, UNSATURATED AROMATIC AMINES | MERCK & CO., INC. (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10243151-B2 | Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same | OXA1L, BECN1, MAP1LC3A | GABRP 379/4885GABRD 162/4885GABRA1 146/4885 |
| US-20240158340-A1 | PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SAME | AHR, CBR3, AADAC | GABRP 4196/4885GABRD 4277/4885GABRA1 3976/4885 |
| US-10174042-B2 | Structure, synthesis, and applications for poly (phenylene) ethynylenes (PPEs) | PGLS, POLI, PARN | GABRP 2716/4885GABRD 2779/4885GABRA1 3257/4885 |
| US-20190116797-A1 | STRUCTURE, SYNTHESIS, AND APPLICATIONS FOR POLY(PHENYLENE ETHYNYLENES) (PPEs) | PGLS, POLI, PARN | GABRP 2746/4885GABRD 2753/4885GABRA1 3250/4885 |
| US-10399961-B2 | Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors | KLKB1, BDKRB1, BDKRB2 | GABRP 4433/4885GABRD 4342/4885GABRA1 4022/4885 |
| US-10750746-B2 | Structure, synthesis, and applications for poly (phenylene) ethynylenes (PPEs) | PGLS, POLI, PARN | GABRP 2716/4885GABRD 2779/4885GABRA1 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.