Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28936935 | 0.98 | ALOX15 (0.50) | CA12CA9CA2ALOX15CA1 | |
| SCHEMBL28721741 | 0.95 | CA12 (0.45) | CA12CA9CA2ALOX15CA1 | |
| SCHEMBL20438627 | 0.90 | CA12 (0.44) | CA12CA9CA2ALOX15CA1 | |
| SCHEMBL995109 | 0.90 | CA12 (0.54) | CA12CA9CA2ALOX15CA1 | |
| SCHEMBL13817382 | 0.89 | CYP2D6 (0.43) | CA12CA9CA2ALOX15CA1 | |
| Ammonia Solution, Strong SCHEMBL28996333 | 0.88 | CA12 (0.53) | CA12CA9CA2ALOX15CA1 | |
| SCHEMBL12378540 | 0.85 | ALDH1A1 (0.42) | CA12CA9CA2ALOX15CA1 | |
| SCHEMBL2336434 | 0.85 | MAPT (0.46) | CA12CA9MAPTMCOLN3C5AR1 | |
| SCHEMBL241884 | 0.85 | CA1 (0.52) | CA12CA9CA2CA1GAA | |
| SCHEMBL2335489 | 0.83 | GLA (0.50) | CA12CA9CA1MAPTMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009957-A1 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK SHARP & DOHME CORP. | 2010-01-14 | — | — | US | disclosed |
| US-20100009957-A1 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK SHARP & DOHME CORP. | 2010-01-14 | — | — | US | disclosed |
| US-20100009957-A1 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK SHARP & DOHME CORP. | 2010-01-14 | — | — | US | disclosed |
| EP-2069347-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | Merck & Co., Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008039420-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK & CO., INC. (US) | 2008-04-03 | — | — | WO | disclosed |
| WO-2008039420-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK & CO., INC. (US) | 2008-04-03 | — | — | WO | disclosed |
| US-7232825-B2 | Phenylaminopyrimidine derivatives and methods of use | CHEN GUOQING P | 2007-06-19 | — | — | US | disclosed |
| US-7232825-B2 | Phenylaminopyrimidine derivatives and methods of use | CHEN GUOQING P | 2007-06-19 | — | — | US | disclosed |
| EP-0897379-B1 | PROCESS FOR CONVERTING A GEMINALLY SUBSTITUTED CYCLOPENTADIENE | DSM NV (NL) | 2001-10-31 | — | — | EP | disclosed |
| US-6137019-A | Process for converting a geminally substituted cyclopentadiene | DSM N.V. (NL) | 2000-10-24 | — | — | US | disclosed |
| WO-1997042160-A1 | CYCLOPENTADIENE COMPOUND WHEREIN TWO OR THREE HETERO ATOMS ARE PRESENT IN THE SUBSTITUENTS | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| WO-1997042162-A1 | CYCLOPENTADIENE COMPOUND SUBSTITUTED WITH BRANCHED ALKYL GROUPS | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| WO-1997042151-A1 | CYCLOPENTADIENE COMPOUND SUBSTITUTED BY CHIRAL GROUPS | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| WO-1997042241-A1 | PROCESS FOR THE PREPARATION OF AN ETHYLENE AND α-OLEFIN COPOLYMER | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| WO-1997042165-A1 | FLUORENE SUBSTITUTED WITH A GROUP COMPRISING A HETERO ATOM | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| WO-1997042164-A1 | INDENE SUBSTITUTED WITH A GROUP COMPRISING A HETERO ATOM | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| WO-1997042147-A1 | CYCLOPENTADIENE COMPOUND SUBSTITUTED BY ARALKYL GROUPS | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| EP-0805142-A1 | Cyclopentadiene compound substituted with a hetero atom-containing group | DSM N.V. (NL) | 1997-11-05 | — | — | EP | disclosed |
| US-5683856-A | CATIONIC AMMONIUM RESIN, ACID GENERATOR, DISSOLUTION INHIBITION | FUJI PHOTO FILM CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0708368-A1 | Positive-working photosensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009957-A1 | NOVEL INHIBITORS OF BETA-LACTAMASE | MGAM, SI, MGAM2 | CA12 2169/4885CA9 556/4885CA2 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.