Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.53 |
| ▸ | CTSB | P07858 | 13/20 | 0.53 |
| ▸ | CTSL | P07711 | 8/20 | 0.53 |
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742158 | 0.84 | CTSS (0.68) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6061195 | 0.84 | CTSS (0.68) | CTSSCTSBCTSLCTSK | |
| SCHEMBL3621113 | 0.83 | CTSS (0.45) | CTSSCTSBCTSLCTSKCTSF | |
| SCHEMBL6738426 | 0.82 | CTSS (0.77) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6738423 | 0.82 | CTSS (0.77) | CTSSCTSBCTSLCTSK | |
| SCHEMBL3619855 | 0.82 | CTSS (0.52) | CTSSCTSBCTSLCTSK | |
| SCHEMBL7656346 | 0.79 | CTSB (0.71) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6741446 | 0.78 | CTSL (0.71) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6741967 | 0.78 | CTSB (0.67) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6741961 | 0.78 | CTSB (0.67) | CTSSCTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662849-B2 | Amidino compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2010-02-16 | — | — | US | disclosed |
| EP-1761485-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering AG (DE) | 2007-03-14 | — | — | EP | disclosed |
| US-20060264464-A1 | Amidino compounds as cysteine protease inhibitors | QUEST DIAGNOSTICS INVESTMENTS LLC | 2006-11-23 | — | — | US | disclosed |
| WO-2004108661-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS (US) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264464-A1 | Amidino compounds as cysteine protease inhibitors | CTSF, CTSB, CTSS | CTSS 3/4885CTSB 2/4885CTSL 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.