Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18342460 | 0.86 | CYP1A2 (0.46) | CYP1A2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL14897914 | 0.86 | ALDH1A1 (0.48) | CYP1A2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL18342357 | 0.85 | CYP1A2 (0.45) | CYP1A2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL28669556 | 0.83 | CYP1A2 (0.44) | CYP1A2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL9756985 | 0.83 | PLK1 (0.46) | CYP1A2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL9757131 | 0.81 | MAOB (0.42) | CYP1A2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL3817775 | 0.80 | AGPAT2 (0.41) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL3621004 | 0.79 | RAB9A (0.53) | CYP1A2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL17864533 | 0.79 | CYP1A2 (0.44) | CYP1A2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL3614007 | 0.78 | AGPAT2 (0.41) | KDM4EALDH1A1HSD17B10HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113818033-B | Electrochemical synthesis method of 2-substituted benzoxazole derivative | 诚达药业股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113818033-A | Electrochemical synthesis method of 2-substituted benzoxazole derivative | 诚达药业股份有限公司 | 2021-12-21 | — | — | CN | disclosed |
| US-20100137298-A1 | Biaryl Sulfonamides and Methods for Using Same | WYETH (US) | 2010-06-03 | — | — | US | disclosed |
| EP-1692124-B1 | BIARYL SULFONAMIDES AS MMP INHIBITORS | WYETH CORP (US) | 2008-10-15 | — | — | EP | disclosed |
| US-7420001-B2 | Biaryl sulfonamides and methods for using same | WYETH (US) | 2008-09-02 | — | — | US | disclosed |
| EP-1692124-A1 | BIARYL SULFONAMIDES AS MMP INHIBITORS | Wyeth (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005061477-A1 | BIARYL SULFONAMIDES AS MMP INHIBITORS | WYETH (US) | 2005-07-07 | — | — | WO | disclosed |
| US-20050143422-A1 | Biaryl sulfonamides and methods for using same | WYETH (US) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137298-A1 | Biaryl Sulfonamides and Methods for Using Same | STS, MMP3, AADAC | CYP1A2 276/4885MAPT 4416/4885RAB9A 3864/4885 |
| US-20050143422-A1 | Biaryl sulfonamides and methods for using same | STS, MMP3, AADAC | CYP1A2 276/4885MAPT 4416/4885RAB9A 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.