Sugi Predict

Sugi Predict / Compounds / SCHEMBL361669

SCHEMBL361669

SCHEMBL361669

O=[C]Cc1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSPA5 P11021 1/20 0.54
▸ TAAR1 Q96RJ0 1/20 0.52
▸ AKR1B1 P15121 1/20 0.52
▸ TSHR P16473 2/20 0.48
▸ HIF1A Q16665 2/20 0.48
▸ CYP2D6 P10635 1/20 0.48
▸ CA12 O43570 6/20 0.45
▸ CA2 P00918 6/20 0.45
▸ IDO1 P14902 2/20 0.45
▸ CA9 Q16790 4/20 0.43
▸ MPO P05164 1/20 0.43
▸ KEAP1 Q14145 1/20 0.43
▸ HTR1A P08908 1/20 0.42
▸ KDM4E B2RXH2 2/20 0.42
▸ HSD17B10 Q99714 2/20 0.42
▸ NPC1 O15118 1/20 0.41
▸ GMNN O75496 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ EGFR P00533 1/20 0.41
▸ LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11480751 0.82 GABRA1 (0.36) HSPA5TAAR1AKR1B1IDO1ALDH1A1
SCHEMBL3239779 0.79 MPO (0.50) HSPA5TAAR1AKR1B1TSHRHIF1A
SCHEMBL911041 0.77 TAAR1 (0.54) HSPA5TAAR1AKR1B1TSHRHIF1A
SCHEMBL30023384 0.76 HSPA5 (0.54) HSPA5TAAR1AKR1B1TSHRHIF1A
SCHEMBL7687789 0.76 APOBEC3G (0.43) TAAR1TSHRALDH1A1LMNAHPGD
SCHEMBL1593309 0.76 HSPA5 (0.54) HSPA5TAAR1AKR1B1TSHRHIF1A
SCHEMBL891289 0.76 HSPA5 (0.54) HSPA5TAAR1AKR1B1TSHRHIF1A
Formaldehyde SCHEMBL28448370 0.76 HSPA5 (0.48) HSPA5TAAR1AKR1B1TSHRHIF1A
SCHEMBL753898 0.74 HSPA5 (0.73) HSPA5TAAR1AKR1B1TSHRHIF1A
SCHEMBL2526586 0.74 HSPA5 (0.73) HSPA5TAAR1AKR1B1TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114105856-B O-hydroxyphenylacetyl spliced bisindolylmethyl compound, and preparation method and application thereof 贵州大学 2023-05-12 — — CN claimed
CN-114105856-A O-hydroxyphenylacetyl spliced bisindolylmethyl compound as well as preparation method and application thereof 贵州大学 2022-03-01 — — CN claimed
CN-111454154-A Euphorbia lathyris diterpene alkane type compound and extraction method and application thereof 沈阳药科大学 2020-07-28 — — CN claimed
CN-104324028-B The transdermal drug delivery system of beta-lactam antibiotic 于崇曦 2019-01-22 — — CN claimed
US-20090300800-A1 D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation BASF PLANT SCIENCE GMBH (DE) 2009-12-03 — — US claimed
US-20070248996-A1 Modulators of beta-amyloid peptide aggregation comprising D-amino acids PARAECIS PHARMACEUTICALS, INC. (US) 2007-10-25 — — US claimed
US-20060014696-A1 Modulators of beta-amyloid peptide aggregation comprising D-amino acids PRAECIS PHARMACEUTICALS, INC. (US) 2006-01-19 — — US claimed
EP-0929574-B1 MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS PRAECIS PHARM INC (US) 2005-06-29 — — EP claimed
EP-0970691-B1 Composition for topical application containing a lipase, vitamin precursor and a fatty alcohol OREAL (FR) 2003-07-16 — — EP claimed
US-6488928-B1 ESTER OF THE HYDROXY ACID HAVING A SATURATED OR UNSATURATED, LINEAR OR BRANCHED CHAIN AND FROM 2 TO 25 CARBON ATOMS; PACKAGED SEPARATELY L'OREAL (FR) 2002-12-03 — — US claimed
US-5985242-A PEPTIDE OF 3 TO 5 D-AMINO ACIDS; MAY BE MODIFIED AT AMINO-AND/OR CARBOXY TERMINUS; FOR TREATMENT OF AMYLOIDOSIS, ALZHEIMER'S DISEASE PRAECIS PHARMACEUTICALS, INC. (US) 1999-11-16 — — US claimed
EP-0929574-A1 MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS Praecis Pharmaceuticals Incorporated (US) 1999-07-21 — — EP claimed
US-5788972-A DIHYDROXYACETONE AND LIPASE ENZYME L'OREAL (FR) 1998-08-04 — — US claimed
WO-1998008868-A9 MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS — 1998-05-28 — — WO claimed
WO-1998008868-A1 MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS PRAECIS PHARMACEUTICALS INCORPORATED (US) 1998-03-05 — — WO claimed
EP-0710478-B1 Composition for topical application containing a lipase and an active agent precursor OREAL (FR) 1997-01-22 — — EP claimed
EP-0713696-A1 Topical application product containing a lipase and a precursor of hydroxyacid L'OREAL (FR) 1996-05-29 — — EP claimed
EP-0710478-A1 Composition for topical application containing a lipase and an active agent precursor L'OREAL (FR) 1996-05-08 — — EP claimed
US-4113946-A Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-09-12 — — US claimed
US-4112230-A Δ2,3 -1,4 Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-09-05 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070248996-A1 Modulators of beta-amyloid peptide aggregation comprising D-amino acids APP, IAPP, BACE1 HSPA5 825/4885TAAR1 3447/4885AKR1B1 2509/4885
US-20060014696-A1 Modulators of beta-amyloid peptide aggregation comprising D-amino acids APP, IAPP, BACE1 HSPA5 825/4885TAAR1 3447/4885AKR1B1 2509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.