SCHEMBL753898

SCHEMBL753898

N=C=O.N=C=O.Oc1ccccc1Cc1ccccc1O

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.73
KEAP1 Q14145 1/20 0.52
AKR1B1 P15121 1/20 0.50
TSHR P16473 2/20 0.46
CYP2D6 P10635 1/20 0.46
HIF1A Q16665 1/20 0.46
TAAR1 Q96RJ0 1/20 0.45
CA12 O43570 5/20 0.43
CA2 P00918 5/20 0.43
IDO1 P14902 2/20 0.43
CA9 Q16790 4/20 0.42
MPO P05164 1/20 0.42
HTR1A P08908 1/20 0.41
IDH1 O75874 1/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2526586 1.00 HSPA5 (0.73) HSPA5KEAP1AKR1B1TSHRCYP2D6
SCHEMBL49745 0.85 HSPA5 (1.00) HSPA5KEAP1AKR1B1TSHRCYP2D6
SCHEMBL29357407 0.85 HSPA5 (1.00) HSPA5KEAP1AKR1B1TSHRCYP2D6
SCHEMBL5852726 0.83 HSPA5 (0.94) HSPA5KEAP1AKR1B1TSHRCYP2D6
Ammonia Solution, Strong SCHEMBL28323965 0.83 HSPA5 (0.94) HSPA5KEAP1AKR1B1TSHRCYP2D6
SCHEMBL29839938 0.83 HSPA5 (0.94) HSPA5KEAP1AKR1B1TSHRCYP2D6
SCHEMBL7809667 0.83 HSPA5 (0.94) HSPA5KEAP1AKR1B1TSHRCYP2D6
Catechol SCHEMBL28203731 0.80 ALDH1A1 (0.62) HSPA5AKR1B1TSHRHIF1ACA12
Catechol SCHEMBL28203735 0.80 ALDH1A1 (0.62) HSPA5AKR1B1TSHRHIF1ACA12
2-Allylphenol SCHEMBL28497652 0.79 GABRA1 (0.48) HSPA5AKR1B1TSHRCYP2D6HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240227234-A1 Polymerization Terminating Layer for Isocyanates Utilized During Manufacturing of Cellulose-Based Products GUARDIAN CHEMICALS INC. (CA) 2024-07-11 US claimed
WO-2024098154-A1 POLYMERIZATION TERMINATING LAYER FOR ISOCYANATES UTILIZED DURING MANUFACTURING OF CELLULOSE-BASED PRODUCTS GUARDIAN CHEMICALS INC. (CA) 2024-05-16 WO claimed
US-20220026411-A1 ANALYTICAL METHODS AND ARRAYS FOR USE IN THE SAME SENZAGEN AB (SE) 2022-01-27 US claimed
EP-3906323-A2 METHOD FOR IDENTIFYING AGENTS CAPABLE OF INDUCING RESPIRATORY SENSITIZATION AND ARRAY AND ANALYTICAL KITS FOR USE IN THE METHOD SenzaGen AB (SE) 2021-11-10 EP claimed
CN-113260715-A Method for identifying agents capable of inducing respiratory sensitization and array and assay kit for use in the method 森扎基因有限责任公司 2021-08-13 CN claimed
WO-2020141204-A2 ANALYTICAL METHODS AND ARRAYS FOR USE IN THE SAME SENZAGEN AB (SE) 2020-07-09 WO claimed
CN-107250793-A Analytical method and arrays for use therein 森扎基因有限责任公司 2017-10-13 CN claimed
US-20170283874-A1 Analytical Methods and Arrays for Use in the Same SENZAGEN AB (SE) 2017-10-05 US claimed
US-20170285010-A1 Analytical Methods and Arrays for Use in the Same SENZAGEN AB (SE) 2017-10-05 US claimed
EP-3224618-A1 ANALYTICAL METHODS AND ARRAYS FOR USE IN THE SAME SenzaGen AB (SE) 2017-10-04 EP claimed
WO-2016083604-A1 ANALYTICAL METHODS AND ARRAYS FOR USE IN THE SAME SENZAGEN AB (SE) 2016-06-02 WO claimed
US-20150111771-A1 Method for Identifying Agents Capable of Inducing Respiratory Sensitization and Array and Analytical Kits for Use in the Method SENZAGEN AB (SE) 2015-04-23 US claimed
EP-2841599-A1 METHOD FOR IDENTIFYING AGENTS CAPABLE OF INDUCING RESPIRATORY SENSITIZATION AND ARRAY AND ANALYTICAL KITS FOR USE IN THE METHOD. Senzagen AB (SE) 2015-03-04 EP claimed
WO-2013160882-A1 METHOD FOR IDENTIFYING AGENTS CAPABLE OF INDUCING RESPIRATORY SENSITIZATION AND ARRAY AND ANALYTICAL KITS FOR USE IN THE METHOD. SENZAGEN AB (SE) 2013-10-31 WO claimed
US-20240227234-A1 Polymerization Terminating Layer for Isocyanates Utilized During Manufacturing of Cellulose-Based Products GUARDIAN CHEMICALS INC. (CA) 2024-07-11 US disclosed
WO-2024098154-A1 POLYMERIZATION TERMINATING LAYER FOR ISOCYANATES UTILIZED DURING MANUFACTURING OF CELLULOSE-BASED PRODUCTS GUARDIAN CHEMICALS INC. (CA) 2024-05-16 WO disclosed
CN-111295441-B Novel cell lines and uses thereof 森扎基因有限责任公司 2024-03-26 CN disclosed
US-20090169812-A1 Process for Making Composite Products from Fibrous Waste Material BUILDING RESEARCH ESTABLISHMENT LTD (GB) 2009-07-02 US disclosed
EP-2001522-A1 PROCESS FOR MAKING COMPOSITE PRODUCTS FROM FIBROUS WASTE MATERIAL Building Research Establishment Ltd (GB) 2008-12-17 EP disclosed
WO-2007110661-A1 PROCESS FOR MAKING COMPOSITE PRODUCTS FROM FIBROUS WASTE MATERIAL BUILDING RESEARCH ESTABLISHMENT LTD (GB) 2007-10-04 WO disclosed