SCHEMBL361719

SCHEMBL361719

c1ccc2c(c1)ncn1nccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.54
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
NCF1 P14598 1/20 0.39
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
POLB P06746 1/20 0.38
BMP4 P12644 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
STAT3 P40763 1/20 0.36
GPR3 P46089 1/20 0.36
FGFR1 P11362 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29974345 1.00 KDM4E (0.54) KDM4ERAB9ANPC1NCF1HTR3E
SCHEMBL31410791 0.79 FGFR1 (0.44) KDM4EFGFR1
SCHEMBL29967853 0.73 KDM4E (0.51) KDM4ERAB9ANPC1NCF1HPGD
SCHEMBL3594951 0.73 KDM4E (0.51) KDM4ERAB9ANPC1NCF1HPGD
SCHEMBL3594952 0.71 KDM4E (0.49) KDM4ERAB9ANPC1NCF1HPGD
SCHEMBL29648618 0.71 KDM4E (0.49) KDM4ERAB9ANPC1NCF1HPGD
SCHEMBL363828 0.71 KDM4E (1.00) KDM4ERAB9ANPC1NCF1HPGD
SCHEMBL11472894 0.68 KDM4E (0.62) KDM4ERAB9ANPC1HPGDHSD17B10
SCHEMBL2511897 0.68 KDM4E (0.42) KDM4ERAB9ANPC1NCF1HPGD
SCHEMBL4788149 0.68 KDM4E (0.46) KDM4ERAB9AHPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4252945-A 4(1H)-QUINOLONES REACTED WITH HYDRAZINE TO FORM 5-(2-AMINOPHENYL)PYRAZOLES WHICH ARE CYCLIZED WITH PHOSGENE, THIOPHOSGENE OR ETHYL CHLOROFORMATE E. R. SQUIBB & SONS, INC. (US) 1981-02-24 US claimed
EP-0023773-A1 Process for preparing pyrazolo(1,5-c)-quinazoline derivatives and novel intermediates E.R. Squibb & Sons, Inc. (US) 1981-02-11 EP claimed
US-20260143900-A1 HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC LAYER INCLUDING THE SAME, AND LIGHT EMITTING DEVICE INCLUDING THE SAME LT MAT CO LTD (KR) 2026-05-21 US disclosed
US-20260136750-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME AND COMPOSITION FOR FORMING ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING DEVICE LT MATERIALS CO LTD (KR) 2026-05-14 US disclosed
US-20260096342-A1 HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC LAYER INCLUDING THE SAME AND LIGHT EMITTING DEVICE INCLUDING THE SAME LT MATERIALS CO LTD (KR) 2026-04-02 US disclosed
US-20260090188-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING DEVICE LT MATERIALS CO LTD (KR) 2026-03-26 US disclosed
US-20260076027-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LT MATERIALS CO LTD (KR) 2026-03-12 US disclosed
EP-4707356-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2026-03-11 EP disclosed
US-20260026190-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME LT MATERIALS CO LTD (KR) 2026-01-22 US disclosed
EP-4682150-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME LT Materials Co., Ltd. (KR) 2026-01-21 EP disclosed
EP-4626204-A1 ORGANIC LIGHT-EMITTING DEVICE, AND COMPOSITION FOR FORMING ORGANIC MATERIAL LAYER LT Materials Co., Ltd. (KR) 2025-10-01 EP disclosed
US-4164578-A ANTIALLERGENS E. R. SQUIBB & SONS, INC. (US) 1979-08-14 US disclosed
US-4128644-A ANTIALLERGENS, ANTIINFLAMMATORY PHOSPHODIESTERASE INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1978-12-05 US disclosed
US-4128644-A ANTIALLERGENS, ANTIINFLAMMATORY PHOSPHODIESTERASE INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1978-12-05 US disclosed
US-4112096-A ANTIALLERGENS E. R. SQUIBB & SONS, INC. (US) 1978-09-05 US disclosed
US-4112096-A ANTIALLERGENS E. R. SQUIBB & SONS, INC. (US) 1978-09-05 US disclosed
US-4112098-A ANTIALLERGENS, ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1978-09-05 US disclosed
US-4112098-A ANTIALLERGENS, ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1978-09-05 US disclosed
US-4110452-A ANTIALLERGENS E. R. SQUIBB & SONS, INC. (US) 1978-08-29 US disclosed
US-4076818-A ANTIALLERGENS E. R. SQUIBB & SONS, INC. (US) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260143900-A1 HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC LAYER INCLUDING THE SAME, AND LIGHT EMITTING DEVICE INCLUDING THE SAME PTGER1, OXER1, CBR1 KDM4E 2137/4885RAB9A 1646/4885NPC1 2441/4885
US-20260026190-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME LBR, CBR1, CRY1 KDM4E 1978/4885RAB9A 2008/4885NPC1 3278/4885
US-20260076027-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CYC1, CRY2 KDM4E 3760/4885RAB9A 2148/4885NPC1 1006/4885
US-20260136750-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME AND COMPOSITION FOR FORMING ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING DEVICE CCNL2, CRY1, CRY2 KDM4E 3529/4885RAB9A 2986/4885NPC1 3363/4885
US-20260090188-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING DEVICE CRY2, CRY1, SCO2 KDM4E 3699/4885RAB9A 1909/4885NPC1 3527/4885
US-20260096342-A1 HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC LAYER INCLUDING THE SAME AND LIGHT EMITTING DEVICE INCLUDING THE SAME CBR1, HCRTR2, GLRA1 KDM4E 1392/4885RAB9A 939/4885NPC1 3018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.