Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 3/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12094224 | 0.85 | TSHR (0.60) | CYP3A4PIM1CA12CA9KDM4E | |
| SCHEMBL511275 | 0.83 | CYP3A4 (0.50) | MAOBCYP3A4PIM1CA12CA1 | |
| SCHEMBL13950674 | 0.82 | LMNA (0.50) | MAOBPIM1KDM4EALDH1A1TSHR | |
| SCHEMBL8765708 | 0.82 | KDM4E (0.62) | CYP3A4PIM1CA12CA2CA9 | |
| SCHEMBL13176949 | 0.82 | ACHE (0.61) | MAOBCYP3A4KDM4EALDH1A1TSHR | |
| SCHEMBL3245649 | 0.82 | PIM1 (0.47) | CYP3A4PIM1CA1CA2KDM4E | |
| SCHEMBL8995644 | 0.81 | MAOB (0.54) | MAOBCA12CA1CA2CA7 | |
| SCHEMBL18130081 | 0.81 | ABCB1 (0.57) | MAOBCYP3A4CA12CA1CA2 | |
| SCHEMBL4274421 | 0.81 | APP (0.43) | MAOBCYP3A4PIM1RAB9APREP | |
| SCHEMBL18130083 | 0.81 | ABCB1 (0.57) | MAOBCYP3A4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11406678-B2 | Simmondsin formulation | Raes, Stefaan (BE) | 2022-08-09 | — | — | US | claimed |
| CN-114144454-A | Improved operating time to open-run time ratio by adding phenolic catalysts to polyaspartic flooring formulations | 科思创有限公司 | 2022-03-04 | — | — | CN | claimed |
| EP-3452095-B1 | SIMMONDSIN FORMULATION | Van Den Driessche Herman (BE) | 2021-04-07 | — | — | EP | claimed |
| EP-3452095-A2 | SIMMONDSIN FORMULATION | Van den Driessche, Herman (BE) | 2019-03-13 | — | — | EP | claimed |
| US-20190070238-A1 | SIMMONDSIN FORMULATION | VAN DEN DRIESSCHE, HERMAN (BE) | 2019-03-07 | — | — | US | claimed |
| WO-2017191501-A2 | SIMMONDSIN FORMULATION | D'OOSTERLYNCK ANDRÉ (BE) | 2017-11-09 | — | — | WO | claimed |
| US-9695278-B2 | Polyester co-phosphonates | FRX POLYMERS, INC. (US) | 2017-07-04 | — | — | US | claimed |
| EP-2867272-A1 | POLYESTER CO-PHOSPHONATES | FRX Polymers, Inc. (US) | 2015-05-06 | — | — | EP | claimed |
| WO-2014005136-A1 | POLYESTER CO-PHOSPHONATES | FRX POLYMERS, INC. (US) | 2014-01-03 | — | — | WO | claimed |
| US-20140000751-A1 | POLYESTER CO-PHOSPHONATES | DOSKOCIL MANUFACTURING COMPANY, INC. | 2014-01-02 | — | — | US | claimed |
| US-4782132-A | Process for producing a copolyester | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-11-01 | — | — | US | claimed |
| CN-114829450-B | Method for producing liquid crystalline polyester and liquid crystalline polyester | 住友化学株式会社 | 2024-08-16 | — | — | CN | disclosed |
| US-11718747-B2 | Nanoparticle containing compositions | EVONIK OPERATIONS GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-20230069551-A1 | METHOD FOR PRODUCING LIQUID CRYSTALLINE POLYESTER AND LIQUID CRYSTALLINE POLYESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-03-02 | — | — | US | disclosed |
| US-11406678-B2 | Simmondsin formulation | Raes, Stefaan (BE) | 2022-08-09 | — | — | US | disclosed |
| US-4782132-A | Process for producing a copolyester | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0286444-A2 | Process for producing a liquid crystalline polyester of a cyclohexanedicarboxylic acid and an aromatic diol | Chisso Corporation (JP) | 1988-10-12 | — | — | EP | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4168980-A | SILVER IMIDAZOLINE-2-THIONE | EASTMAN KODAK COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-3985564-A | Photographic element and process for developing | EASTMAN KODAK COMPANY (US) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190070238-A1 | SIMMONDSIN FORMULATION | SPIN2B, SNCA, CHKB | MAOB 288/4885CYP3A4 2789/4885PIM1 4389/4885 |
| US-11406678-B2 | Simmondsin formulation | SPIN2B, SNCA, CHKB | MAOB 288/4885CYP3A4 2789/4885PIM1 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.