SCHEMBL3617372

SCHEMBL3617372

ClC(Cl)c1scc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.37
KMT2A Q03164 7/20 0.37
ALDH1A1 P00352 3/20 0.36
LMNA P02545 3/20 0.36
HPGD P15428 1/20 0.36
PRKCZ Q05513 1/20 0.36
CYP2A6 P11509 2/20 0.35
MAPK1 P28482 1/20 0.35
CYP2B6 P20813 1/20 0.35
TSHR P16473 2/20 0.34
DAPK3 O43293 1/20 0.34
PRKD3 O94806 1/20 0.34
MAP4K4 O95819 1/20 0.34
ABL1 P00519 1/20 0.34
NTRK1 P04629 1/20 0.34
LCK P06239 1/20 0.34
CSF1R P07333 1/20 0.34
RET P07949 1/20 0.34
MET P08581 1/20 0.34
PDGFRB P09619 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8219401 0.75 ALDH1A1 (0.49) MEN1KMT2AALDH1A1LMNAHPGD
SCHEMBL9631570 0.73 BCAT2 (0.43) ALDH1A1HPGDCYP2A6MAPK1CYP2B6
SCHEMBL12912902 0.72 CYP2A6 (0.43) MEN1KMT2AALDH1A1LMNAHPGD
SCHEMBL6036925 0.72 BACE1 (0.41) MEN1KMT2AALDH1A1LMNAHPGD
SCHEMBL27836567 0.71 CYP2A6 (0.47) MEN1KMT2AALDH1A1LMNAHPGD
Phosphine SCHEMBL28718427 0.71 BACE1 (0.41) MEN1KMT2AALDH1A1LMNAHPGD
SCHEMBL10568574 0.71 PTGS1 (0.49) MEN1KMT2AALDH1A1LMNAHPGD
SCHEMBL2286545 0.71 CYP2A6 (0.38) MEN1KMT2AALDH1A1LMNAHPGD
SCHEMBL11678420 0.71 CYP2A6 (0.38) MEN1KMT2AALDH1A1LMNAHPGD
SCHEMBL12912904 0.69 ALDH1A1 (0.37) MEN1KMT2AALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1548044-B1 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same IMEC (BE) 2013-07-03 EP disclosed
US-7666978-B2 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same IMEC (BE) 2010-02-23 US disclosed
US-20090270575-A1 METHOD OF PREPARING DERIVATIVES OF POLYARYLENE VINYLENE AND METHOD OF PREPARING AN ELECTRONIC DEVICE INCLUDING SAME INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2009-10-29 US disclosed
US-20090183767-A1 METHOD OF PREPARING DERIVATIVES OF POLYARYLENE VINYLENE AND METHOD OF PREPARING AN ELECTRONIC DEVICE INCLUDING SAME INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2009-07-23 US disclosed
US-7511116-B2 polymer from a dihalo arylene and a dithiocarbamic acid sodium salt producing p-xylylene bis(N,N-diethyl dithiocarbamate); plastic electronics INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2009-03-31 US disclosed
US-7446164-B2 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2008-11-04 US disclosed
US-20080045684-A1 METHOD OF PREPARING DERIVATIVES OF POLYARYLENE VINYLENE AND METHOD OF PREPARING AN ELECTRONIC DEVICE INCLUDING SAME INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2008-02-21 US disclosed
US-20070287816-A1 METHOD OF PREPARING DERIVATIVES OF POLYARYLENE VINYLENE AND METHOD OF PREPARING AN ELECTRONIC DEVICE INCLUDING SAME INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2007-12-13 US disclosed
US-7259228-B2 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2007-08-21 US disclosed
US-20050159581-A1 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same LIMBURGS UNIVERSITAIR CENTRUM (BE) 2005-07-21 US disclosed
EP-1548044-A2 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM VZW (BE) 2005-06-29 EP disclosed
EP-1529794-A1 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM VZW (BE) 2005-05-11 EP disclosed