Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Cinnamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.64 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | F3 | P13726 | 2/20 | 0.64 |
| ▸ | TNKS | O95271 | 1/20 | 0.64 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.64 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamic Acid SCHEMBL361738 | 1.00 | MAPT (0.64) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL28100498 | 0.98 | MAPT (0.61) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL122245 | 0.98 | MAPT (0.67) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL10899356 | 0.98 | MAPT (0.67) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL122244 | 0.98 | MAPT (0.67) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL10899352 | 0.98 | MAPT (0.67) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL9580385 | 0.95 | MAPT (0.64) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL6916885 | 0.95 | MAPT (0.64) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL6444117 | 0.95 | MAPT (0.64) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL2687216 | 0.95 | MAPT (0.64) | MAPTHDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 832 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120117619-A | Method for adjusting acid center of molecular sieve at fixed point | 中国石油化工股份有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-119908385-A | Antibacterial and mildew-proof composition for food, and product and application thereof | 广州海有生物科技有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119818406-A | Pummelo peel polyphenol hybrid liposome and preparation method thereof, and skin moisturizing lotion and preparation method thereof | 中国热带农业科学院农产品加工研究所 | 2025-04-15 | — | — | CN | claimed |
| CN-119836105-A | Perovskite battery and preparation method thereof | 旗滨新能源发展(深圳)有限责任公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119744708-A | Method for preventing and treating grape yellow leaf | 河北萌帮水溶肥料股份有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119633126-A | Capsule skin composition containing sanzan gum and preparation method and application thereof | 廊坊梅花生物技术开发有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119078314-A | Waterproof ultraviolet-resistant composite fabric and preparation method thereof | 海安润腾纺织科技有限公司 | 2024-12-06 | — | — | CN | claimed |
| CN-118872439-A | Saline-alkali soil improvement method | 华清农业开发有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-221934118-U | Swinging pulverizer for potassium cinnamate raw material production | 武汉能迈科香料有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118614601-A | Preservative emulsifying composition and application thereof | 苏州闻达食品配料有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-1256404-C | Light controllable orientated liquid crystal polymer containing photosensitive group of cinnyl and its synthesis | UNIV NANKAI (CN) | 2006-05-17 | — | — | CN | claimed |
| CN-1613966-A | Light controllable orientated liquid crystal polymer containing photosensitive group of cinnyl and its synthesis | UNIV NANKAI (CN) | 2005-05-11 | — | — | CN | claimed |
| CN-1334794-A | Process for preparation of methyl p-vinylbenzoate and p-vinyl benzoic acid, and their use in latex compositions | EASTMAN CHEM CO (US) | 2002-02-06 | — | — | CN | claimed |
| US-20020007010-A1 | Process for the preparation of methyl p-vinylbenzoate and p-vinyl benzoic acid, and their use in latex compositions | EASTMAN CHEMICAL COMPANY | 2002-01-17 | — | — | US | claimed |
| US-6313340-B1 | Process for the preparation of methyl p-vinylbenzoate and p-vinyl benzoic acid, and their use in latex compositions | EASTMAN CHEMICAL CORPORATION | 2001-11-06 | — | — | US | claimed |
| EP-1140771-A1 | PROCESS FOR THE PREPARATION OF METHYL P-VINYLBENZOATE AND P-VINYL BENZOIC ACID, AND THEIR USE IN LATEX COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2001-10-10 | — | — | EP | claimed |
| CN-1303672-A | Application of cinnamate in preparation of medicine for curing diabetes | HUNAN BRANCH CO YUKANG INDUSTR (CN) | 2001-07-18 | — | — | CN | claimed |
| WO-2000069282-A1 | MODIFICATION OF THE TASTE AND PHYSICOCHEMICAL PROPERTIES OF NEOTAME USING HYDROPHOBIC ACID ADDITIVES | THE NUTRASWEET COMPANY (US) | 2000-11-23 | — | — | WO | claimed |
| WO-2000035850-A1 | PROCESS FOR THE PREPARATION OF METHYL P-VINYLBENZOATE AND P-VINYL BENZOIC ACID, AND THEIR USE IN LATEX COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2000-06-22 | — | — | WO | claimed |
| US-5554374-A | Skin preparation using nanospheres | COSMETICS DEVELOPMENT COMPANY LIMITED (GB) | 1996-09-10 | — | — | US | claimed |