SCHEMBL361743

SCHEMBL361743

N#Cc1ccc2scnc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
HSD17B10 Q99714 1/20 0.45
KDM4E B2RXH2 3/20 0.40
HKDC1 Q2TB90 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ESR1 P03372 1/20 0.39
DYRK1A Q13627 2/20 0.38
PPARA Q07869 1/20 0.38
HSD11B1 P28845 1/20 0.37
APP P05067 1/20 0.36
GAA P10253 2/20 0.36
PFKFB3 Q16875 1/20 0.36
MEN1 O00255 1/20 0.36
PPARG P37231 1/20 0.36
PPP1CA P62136 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3310695 0.87 L3MBTL1 (0.42) ALDH1A1HSD17B10KDM4EHKDC1TDP1
SCHEMBL1799071 0.86 KDM4E (0.49) ALDH1A1HSD17B10KDM4EHKDC1TDP1
SCHEMBL3301358 0.86 FFAR1 (0.45) ALDH1A1HSD17B10DYRK1AMAP4K4LIMK1
SCHEMBL31070287 0.82 CYP19A1 (0.42) ALDH1A1HSD17B10KDM4ERAB9AMEN1
SCHEMBL26790748 0.81 ALDH1A1 (0.45) ALDH1A1HSD17B10KDM4EHKDC1TDP1
SCHEMBL6477863 0.81 ALDH1A1 (0.45) ALDH1A1HSD17B10KDM4EHKDC1TDP1
SCHEMBL3301463 0.80 PFKFB3 (0.40) ALDH1A1HSD17B10DYRK1APFKFB3ADORA2A
SCHEMBL1850817 0.80 KDM4E (0.42) ALDH1A1KDM4EL3MBTL1DYRK1APFKFB3
SCHEMBL3306715 0.76 CYP11B1 (0.50) DYRK1AMAP4K4TGFBR1
SCHEMBL13394608 0.75 APP (0.40) ALDH1A1HSD17B10KDM4EHKDC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397629-B1 METALLOENZYME INHIBITOR COMPOUNDS NQP 1598 LTD (KY) 2023-04-19 EP claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US claimed
WO-2024044098-A2 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-29 WO disclosed
EP-3183250-B1 PROCESS FOR PREPARING CRYSTALLINE ORGANIC SEMICONDUCTOR MATERIAL CLAP CO LTD (KR) 2023-10-04 EP disclosed
EP-3397629-B1 METALLOENZYME INHIBITOR COMPOUNDS NQP 1598 LTD (KY) 2023-04-19 EP disclosed
WO-2023001061-A1 CDK7 SELECTIVE INHIBITORS AS ANTICANCER AGENTS JINGRUI BIOPHARMA CO., LTD. (CN) 2023-01-26 WO disclosed
EP-3183757-B1 ORGANIC SEMICONDUCTOR COMPOSITION COMPRISING LIQUID MEDIUM CLAP CO LTD (KR) 2022-05-04 EP disclosed
WO-2022022680-A1 NITROGEN-CONTAINING FUSED RING DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2022-02-03 WO disclosed
US-11193065-B2 Liquid crystal composition, method of producing the same, and retardation film constituted from the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-12-07 US disclosed
CN-107004768-B Organic semiconductor composition containing a liquid medium 巴斯夫欧洲公司 2020-08-21 CN disclosed
US-4040841-A SENSITIZING DYE FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4018610-A Supersensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1977-04-19 US disclosed
US-4010037-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1977-03-01 US disclosed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US disclosed
US-3977883-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US disclosed
US-3973969-A Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-08-10 US disclosed
US-3967967-A CYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-07-06 US disclosed
US-3966477-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR ALDH1A1 4757/4885HSD17B10 4363/4885KDM4E 3646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.