SCHEMBL1799071

SCHEMBL1799071

N#Cc1ccc2ncsc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
HKDC1 Q2TB90 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
ALDH1A1 P00352 2/20 0.47
HSD17B10 Q99714 1/20 0.47
DYRK1A Q13627 2/20 0.46
APP P05067 4/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
PFKFB3 Q16875 1/20 0.42
GAA P10253 1/20 0.42
PPARG P37231 1/20 0.42
PPP1CA P62136 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
NR2E3 Q9Y5X4 1/20 0.42
NCOR2 Q9Y618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL361743 0.86 ALDH1A1 (0.45) KDM4EHKDC1TDP1L3MBTL1NPC1
SCHEMBL23480172 0.83 NPC1 (0.52) KDM4EHKDC1TDP1L3MBTL1NPC1
SCHEMBL3310695 0.82 L3MBTL1 (0.42) KDM4EHKDC1TDP1L3MBTL1NPC1
SCHEMBL2586408 0.81 ADORA2A (0.56) ALDH1A1HSD17B10DYRK1AMEN1KMT2A
SCHEMBL3396673 0.80 NPC1 (0.53) KDM4EHKDC1TDP1L3MBTL1NPC1
SCHEMBL3032150 0.80 NPC1 (0.49) KDM4EHKDC1TDP1L3MBTL1NPC1
SCHEMBL12230276 0.79 PFKFB3 (0.43) KDM4EHKDC1TDP1L3MBTL1NPC1
SCHEMBL3301358 0.77 FFAR1 (0.45) ALDH1A1HSD17B10DYRK1ATGFBR1MAP4K4
Benzo[D]Thiazole SCHEMBL28804971 0.76 ALDH1A1 (0.68) KDM4EHKDC1TDP1L3MBTL1NPC1
SCHEMBL2593553 0.74 MAP4K4 (0.55) DYRK1AAPPADORA2ATGFBR1MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397629-B1 METALLOENZYME INHIBITOR COMPOUNDS NQP 1598 LTD (KY) 2023-04-19 EP claimed
CN-115504942-A Synthesis method of alkyl or acyl substituted benzothiazole derivative 汕头大学 2022-12-23 CN claimed
CN-109517162-A Injectable hydrogel and preparation method thereof 南京工业大学 2019-03-26 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-1226555-A Antifungal agent, and preparation method and intermediate thereof 1999-08-25 CN claimed
EP-0667346-A2 Azole antifungal agents, process for the preparation there of and intermediates Eisai Co., Ltd. (JP) 1995-08-16 EP claimed
CN-118019735-A Arylsulfonyl compounds as CCR6 inhibitors 坎莫森特里克斯公司 2024-05-10 CN disclosed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN disclosed
WO-2023229375-A1 HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF 주식회사 엘지화학 2023-11-30 WO disclosed
EP-3183250-B1 PROCESS FOR PREPARING CRYSTALLINE ORGANIC SEMICONDUCTOR MATERIAL CLAP CO LTD (KR) 2023-10-04 EP disclosed
EP-3397629-B1 METALLOENZYME INHIBITOR COMPOUNDS NQP 1598 LTD (KY) 2023-04-19 EP disclosed
CN-115504942-A Synthesis method of alkyl or acyl substituted benzothiazole derivative 汕头大学 2022-12-23 CN disclosed
US-5789429-A FUNGICIDE EISAI CO., LTD. (JP) 1998-08-04 US disclosed
US-5648372-A TRIAZOLES EISAI CO., LTD. (JP) 1997-07-15 US disclosed
US-5523312-A ADMINISTERING TO MAMMALS STERLING WINTHROP INC. (US) 1996-06-04 US disclosed
US-5514692-A VIRICIDES STERLING WINTHROP INC. (US) 1996-05-07 US disclosed
WO-1996009822-A1 ANTIPICORNAVIRAL AGENTS SANOFI WINTHROP, INC. (US) 1996-04-04 WO disclosed
US-5484926-A VIRICIDES AND ENZYME INHIBITORS AGOURON PHARMACEUTICALS, INC. (US) 1996-01-16 US disclosed
EP-0667346-A2 Azole antifungal agents, process for the preparation there of and intermediates Eisai Co., Ltd. (JP) 1995-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR KDM4E 3646/4885HKDC1 2888/4885TDP1 3713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.