Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2457599 | 0.73 | NPC1 (0.51) | NPSR1NPC1MAPTCYP11B1CYP11B2 | |
| SCHEMBL10051451 | 0.73 | CYP1A2 (0.70) | CYP1A2ALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL12655974 | 0.73 | CYP1A2 (0.59) | CYP1A2ALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL27962029 | 0.72 | ALDH1A1 (1.00) | CYP1A2ALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL10051442 | 0.71 | CYP1A2 (0.62) | CYP1A2ALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL30239993 | 0.71 | ESR1 (0.71) | CYP1A2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15902840 | 0.71 | ESR1 (0.71) | CYP1A2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30603836 | 0.71 | ESR1 (0.71) | CYP1A2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5013872 | 0.71 | ESR1 (0.71) | CYP1A2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL239121 | 0.71 | ESR1 (0.71) | CYP1A2ALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552257-A | 3, 5-disubstituted isothiazole compound and synthesis method and application thereof | 五邑大学 | 2021-03-26 | — | — | CN | claimed |
| CN-112552257-A | 3, 5-disubstituted isothiazole compound and synthesis method and application thereof | 五邑大学 | 2021-03-26 | — | — | CN | disclosed |
| US-20100317703-A1 | METHOD FOR INHIBITING BRASSININ OXIDASE | UNIVERSITY OF SASKATCHEWAN (CA) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317703-A1 | METHOD FOR INHIBITING BRASSININ OXIDASE | BROX, BLVRB, BBOX1 | CYP1A2 1667/4885ALDH1A1 3166/4885CYP2C9 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.