SCHEMBL1401854

SCHEMBL1401854

C=CC(=O)Oc1ccc(CCCC)cc1

nearest known ligand 0.91

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 11/20 0.91
▸ THRA P10827 8/20 0.61
▸ MEN1 O00255 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ HPGD P15428 2/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ TSHR P16473 1/20 0.49
▸ RARB P10826 1/20 0.46
▸ PLK1 P53350 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL823056 0.95 THRB (0.83) THRBTHRAMEN1KMT2AHPGD
SCHEMBL11031162 0.95 THRB (1.00) THRBTHRAMEN1KMT2AHPGD
SCHEMBL28432245 0.94 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL10651481 0.94 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL28428730 0.94 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL6931228 0.94 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL4475071 0.94 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL2289080 0.94 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL187096 0.94 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL13614374 0.93 THRB (0.78) THRBTHRAMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180346629-A1 Biocompatible polymers and co-polymers, and uses thereof GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2018-12-06 — — US claimed
EP-2292672-B1 Biocompatible polymers and co-polymers comprising amino acids in the side chain CIS PHARMA AG (CH) 2018-05-09 — — EP claimed
US-20170152335-A1 Biocompatible polymers and co-polymers, and uses thereof HITZ HANS (CH) 2017-06-01 — — US claimed
EP-1888660-B1 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN CIS PHARMA AG (CH) 2017-05-17 — — EP claimed
US-8980957-B2 Methods for the preparation of biocompatible polymers, the polymers and their uses CIS PHARMA AG (CH) 2015-03-17 — — US claimed
US-20140242722-A1 ARTICLE AND METHOD FOR DETECTION OF A DRUG IN A LIQUID MEDIUM MEDTECH DETECT, LLC (US) 2014-08-28 — — US claimed
WO-2014062910-A1 SPIROPYRAN-BASED COLORIMETRIC DETECTION MEDTECH DETECT, LLC (US) 2014-04-24 — — WO claimed
US-20120329902-A1 METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES SCHAEFER ROLF (CH) 2012-12-27 — — US claimed
EP-2523982-A1 METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES Chemisches Institut Schaefer AG (CH) 2012-11-21 — — EP claimed
WO-2011085988-A1 METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES CHEMISCHES INSTITUT SCHAEFER AG (CH) 2011-07-21 — — WO claimed
EP-2292672-A2 Biocompatible polymers and co-polymers comprising amino acids in the side chain Chemisches Institut Schaefer AG (CH) 2011-03-09 — — EP claimed
US-20090232871-A1 Biocompatible polymers and co-polymers, and uses thereof HITZ HANS 2009-09-17 — — US claimed
EP-1888660-A2 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN Chemisches Institut Schaefer AG (CH) 2008-02-20 — — EP claimed
EP-1861735-A2 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M Innovative Properties Company (US) 2007-12-05 — — EP claimed
WO-2006126095-A2 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN CHEMISCHES INSTITUT SCHAEFER AG (CH) 2006-11-30 — — WO claimed
WO-2006099357-A2 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-09-21 — — WO claimed
EP-4267708-B1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS INFINEUM INT LTD (GB) 2025-07-02 — — EP disclosed
US-12281203-B2 Thermally responsive brush polymers having a copolymer backbone and copolymer arms INFINEUM INTERNATIONAL LIMITED (GB) 2025-04-22 — — US disclosed
WO-1999028402-A1 REPOSITIONABLE SHEETS WITH A NONWOVEN WEB OF PRESSURE-SENSITIVE ADHESIVE FIBERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-10 — — WO disclosed
EP-0843218-A1 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1998-05-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090232871-A1 Biocompatible polymers and co-polymers, and uses thereof PPIH, ARG1, P4HA1 THRB 3915/4885THRA 3777/4885MEN1 3698/4885
US-20170152335-A1 Biocompatible polymers and co-polymers, and uses thereof ARG1, CRYAA, COL1A1 THRB 4338/4885THRA 3671/4885MEN1 1846/4885
US-20180346629-A1 Biocompatible polymers and co-polymers, and uses thereof ARG1, CRYAA, COL1A1 THRB 4338/4885THRA 3671/4885MEN1 1846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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