Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304423 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HSD17B10CES2CES1THRB | |
| SCHEMBL3617593 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HSD17B10CES2CES1THRB | |
| SCHEMBL105254 | 1.00 | — | — | |
| SCHEMBL3627050 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HSD17B10CES2CES1THRB | |
| SCHEMBL3620835 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HSD17B10CES2CES1THRB | |
| SCHEMBL15373185 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HSD17B10CES2CES1THRB | |
| SCHEMBL42570 | 1.00 | — | — | |
| SCHEMBL303089 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HSD17B10CES2CES1THRB | |
| SCHEMBL103932 | 1.00 | — | — | |
| SCHEMBL3622611 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HSD17B10CES2CES1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019023501-A1 | UNIVERSAL ABT COMPOUNDS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-01-31 | — | — | WO | disclosed |
| US-8669375-B2 | Process for producing ester compound | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-11 | — | — | US | disclosed |
| US-20130066070-A1 | PROCESS FOR PRODUCING ESTER COMPOUND | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-8318964-B2 | Process for producing ester compound | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-8093206-B2 | Methods involving long lasting synthetic exendin-4 peptide conjugates | CONJUCHEM, LLC (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100324314-A1 | PROCESS FOR PRODUCING ESTER COMPOUND | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| WO-2010023216-A1 | VACCINE | GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) | 2010-03-04 | — | — | WO | disclosed |
| US-20090075890-A1 | Long lasting synthetic exendin-4 peptide conjugates and methods of use thereof | CONJUCHEM BIOTECHNOLOGIES INC. | 2009-03-19 | — | — | US | disclosed |
| US-3994979-A | FROM S AND MERCAPTIDE OBTAINED FROM REACTION OF THIOL WITH 1A HYDROXIDE | PHILLIPS PETROLEUM COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130066070-A1 | PROCESS FOR PRODUCING ESTER COMPOUND | ADH1C, ADH5, ADH1A | ALDH1A1 261/4885HSD17B10 47/4885CES2 185/4885 |
| US-20090075890-A1 | Long lasting synthetic exendin-4 peptide conjugates and methods of use thereof | IAPP, VIP, GLP1R | ALDH1A1 4121/4885HSD17B10 4312/4885CES2 2013/4885 |
| US-20100324314-A1 | PROCESS FOR PRODUCING ESTER COMPOUND | ADH1C, ADH5, ADH1A | ALDH1A1 252/4885HSD17B10 32/4885CES2 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.