Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983571 | 0.92 | ALDH1A1 (0.34) | TP53EPHX2NR1H4ALDH1A1P2RX7 | |
| SCHEMBL983573 | 0.90 | ALDH1A1 (0.35) | TP53EPHX2NR1H4ALDH1A1P2RX7 | |
| SCHEMBL981199 | 0.90 | ALDH1A1 (0.36) | TP53EPHX2NR1H4ALDH1A1P2RX7 | |
| SCHEMBL983569 | 0.87 | ALDH1A1 (0.48) | TP53EPHX2NR1H4ALDH1A1P2RX7 | |
| SCHEMBL980947 | 0.87 | ALDH1A1 (0.38) | TP53EPHX2NR1H4ALDH1A1P2RX7 | |
| SCHEMBL979491 | 0.86 | HSD11B1 (0.35) | TP53EPHX2NR1H4P2RX7HSD11B1 | |
| SCHEMBL980955 | 0.86 | HSD11B1 (0.35) | TP53EPHX2NR1H4P2RX7HSD11B1 | |
| SCHEMBL12948804 | 0.83 | ALDH1A1 (0.37) | TP53EPHX2NR1H4ALDH1A1P2RX7 | |
| SCHEMBL980695 | 0.82 | — | — | |
| SCHEMBL980752 | 0.81 | CA1 (0.31) | EPHX2NR1H4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2199287-A1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2010-06-23 | — | — | EP | disclosed |