Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983569 | 0.92 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1HSD11B1MAPTLMNA | |
| SCHEMBL983573 | 0.90 | ALDH1A1 (0.35) | ALDH1A1HSD11B1LMNAEPHX2NR1H4 | |
| SCHEMBL981199 | 0.90 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1HSD11B1MAPTEPHX2 | |
| SCHEMBL983571 | 0.88 | ALDH1A1 (0.34) | ALDH1A1HSD11B1MAPTLMNAEPHX2 | |
| SCHEMBL979491 | 0.87 | HSD11B1 (0.35) | HSD11B1LMNAEPHX2NR1H4P2RX7 | |
| SCHEMBL980955 | 0.87 | HSD11B1 (0.35) | HSD11B1LMNAEPHX2NR1H4P2RX7 | |
| SCHEMBL3620024 | 0.87 | TP53 (0.35) | ALDH1A1HSD11B1MAPTEPHX2NR1H4 | |
| SCHEMBL12948804 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HSD11B1MAPTLMNAEPHX2 | |
| SCHEMBL980752 | 0.80 | CA1 (0.31) | EPHX2NR1H4 | |
| SCHEMBL16888428 | 0.80 | CA1 (0.36) | HSD11B1MAPTLMNAEPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318757-B2 | Substituted isoxazoline compound and pest control agent | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20110009438-A1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009438-A1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | CCR10, H1-10, CCL11 | ALDH1A1 3126/4885L3MBTL1 103/4885HSD11B1 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.