Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 3/20 | 0.33 |
| ▸ | FABP3 | P05413 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980947 | 0.92 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1HSD11B1MAPTPOLB | |
| SCHEMBL983573 | 0.90 | ALDH1A1 (0.35) | ALDH1A1HSD11B1TP53EPHX2NR1H4 | |
| SCHEMBL981199 | 0.90 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1HSD11B1MAPTPOLB | |
| SCHEMBL983571 | 0.88 | ALDH1A1 (0.34) | ALDH1A1HSD11B1MAPTPOLBTP53 | |
| SCHEMBL980955 | 0.87 | HSD11B1 (0.35) | HSD11B1TP53EPHX2NR1H4LMNA | |
| SCHEMBL979491 | 0.87 | HSD11B1 (0.35) | HSD11B1TP53EPHX2NR1H4LMNA | |
| SCHEMBL3620024 | 0.87 | TP53 (0.35) | ALDH1A1HSD11B1MAPTTP53EPHX2 | |
| SCHEMBL12948804 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HSD11B1MAPTPOLBTP53 | |
| SCHEMBL2523771 | 0.82 | CNR1 (0.34) | ALDH1A1HSD11B1TP53LMNAP2RX7 | |
| SCHEMBL2189026 | 0.81 | CA1 (0.35) | ALDH1A1HSD11B1MAPTTP53EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318757-B2 | Substituted isoxazoline compound and pest control agent | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20110009438-A1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009438-A1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | CCR10, H1-10, CCL11 | ALDH1A1 3126/4885L3MBTL1 103/4885HSD11B1 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.