Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL449698 | 0.86 | HDAC4 (0.73) | TSHRKMT2AMAPTALOX15HPGD | |
| SCHEMBL30214364 | 0.83 | TSHR (0.50) | TSHRKMT2AMAPTALOX15HPGD | |
| SCHEMBL29617026 | 0.82 | HDAC4 (0.64) | TSHRKMT2AMAPTALOX15HPGD | |
| SCHEMBL2075850 | 0.81 | HDAC4 (0.58) | TSHRKMT2AMAPTALOX15HPGD | |
| SCHEMBL669793 | 0.81 | HDAC4 (0.62) | TSHRMAPTHPGDHDAC4HDAC6 | |
| SCHEMBL18013746 | 0.80 | TSHR (0.57) | TSHRKMT2AMAPTALOX15HPGD | |
| SCHEMBL1828976 | 0.79 | HDAC4 (0.65) | TSHRKMT2AMAPTALOX15HPGD | |
| SCHEMBL28427399 | 0.79 | HDAC4 (0.65) | TSHRKMT2AMAPTHPGDHDAC4 | |
| SCHEMBL2632284 | 0.79 | HDAC4 (0.60) | TSHRKMT2AMAPTALOX15HPGD | |
| SCHEMBL14052281 | 0.79 | HDAC4 (0.70) | TSHRKMT2AMAPTHPGDHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116474826-B | Preparation method and application of polyaniline-loaded palladium nanoparticle catalyst | 华南理工大学 | 2025-06-10 | — | — | CN | claimed |
| CN-119930868-A | Catalyst component containing furoic acid ester compound, preparation method thereof, olefin polymerization catalyst, olefin polymerization method and olefin polymer | 中国石油化工股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-116474826-A | Preparation method and application of polyaniline-loaded palladium nanoparticle catalyst | 华南理工大学 | 2023-07-25 | — | — | CN | claimed |
| EP-3710428-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-03-25 | — | — | EP | disclosed |
| EP-4678632-A1 | METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP | AGC Inc. (JP) | 2026-01-14 | — | — | EP | disclosed |
| US-12485109-B2 | Pyrrolo 12.3-dipyrimidine compounds and analogues thereof | BIOCRYST PHARMACEUTICALS, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| US-20250346557-A1 | METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP | AGC Inc. (JP) | 2025-11-13 | — | — | US | disclosed |
| US-12325702-B2 | ATF6 inhibitors and uses thereof | ALTOS LABS, INC. (US) | 2025-06-10 | — | — | US | disclosed |
| CN-116474826-B | Preparation method and application of polyaniline-loaded palladium nanoparticle catalyst | 华南理工大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-116474826-B | Preparation method and application of polyaniline-loaded palladium nanoparticle catalyst | 华南理工大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-119930868-A | Catalyst component containing furoic acid ester compound, preparation method thereof, olefin polymerization catalyst, olefin polymerization method and olefin polymer | 中国石油化工股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| US-4960777-A | Anxiolytic agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0372470-A2 | Novel alpha-cyano-beta-oxopropionamides | CIBA-GEIGY AG (CH) | 1990-06-13 | — | — | EP | disclosed |
| US-4927947-A | Ethynylheteroaromatic-acids having retinoic acid-like activity | ALLERGAN, INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4923884-A | Ethynylheteroaromatic-acids having retinoic acid-like activity | ALLERGAN, INC. (US) | 1990-05-08 | — | — | US | disclosed |
| US-4877792-A | ANXIOLYTIC AGENTS; ANTICONVULSANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-31 | — | — | US | disclosed |
| EP-0272921-A1 | Ethynylheteroaromatic acids having retinoic acid-like activity | ALLERGAN, INC (US) | 1988-06-29 | — | — | EP | disclosed |
| US-4728666-A | Heteroaromatic acetylenes useful as antihypertensive agents | MCNEILAB, INC. (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0226447-A2 | Heteroaromatic acetylenes useful as antihypertensive agents | McNeilab, Inc. (US) | 1987-06-24 | — | — | EP | disclosed |
| US-4663334-A | Heteroaromatic acetylenes useful as antihypertensive agents | MCNEILAB, INC. (US) | 1987-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12325702-B2 | ATF6 inhibitors and uses thereof | ATF4, XBP1, ATF1 | TSHR 3803/4885KMT2A 3989/4885MAPT 264/4885 |
| US-12485109-B2 | Pyrrolo 12.3-dipyrimidine compounds and analogues thereof | C5, DPYD, C9 | TSHR 3862/4885KMT2A 4273/4885MAPT 3029/4885 |
| US-20250346557-A1 | METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP | STS, TST, CYP3A5 | TSHR 423/4885KMT2A 944/4885MAPT 4632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.