Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29046756 | 0.77 | CA2 (0.38) | ALDH1A1TSHRTDP1ALOX12CA2 | |
| Hydrochloric Acid SCHEMBL23795288 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28900454 | 0.64 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Biphenyl SCHEMBL3277135 | 0.61 | ALDH1A1 (0.82) | ALDH1A1TDP1CA1CA2LMNA | |
| Biphenyl SCHEMBL2972554 | 0.61 | ALDH1A1 (0.82) | ALDH1A1TDP1CA1CA2LMNA | |
| Biphenyl SCHEMBL27590086 | 0.61 | ALDH1A1 (0.82) | ALDH1A1TDP1CA1CA2LMNA | |
| Biphenyl SCHEMBL3792980 | 0.61 | ALDH1A1 (0.82) | ALDH1A1TDP1CA1CA2LMNA | |
| Biphenyl SCHEMBL17844626 | 0.61 | ALDH1A1 (0.82) | ALDH1A1TDP1CA1CA2LMNA | |
| Biphenyl SCHEMBL27571804 | 0.61 | ALDH1A1 (0.82) | ALDH1A1TSHRTDP1CA1CA2 | |
| Biphenyl SCHEMBL27523782 | 0.61 | ALDH1A1 (0.82) | ALDH1A1TDP1CA1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644455-B1 | ADHESION ENHANCING COATING COMPOSITION, PROCESS FOR USING AND COATED OR LAMINATED ARTICLES PRODUCED | TRANSITIONS OPTICAL INC (US) | 2016-05-11 | — | — | EP | claimed |
| CN-100513501-C | Adhesion enhancing coating compositions, methods of using the same and coated or laminated articles produced therefrom | TRANSITIONS OPTICAL INC (US) | 2009-07-15 | — | — | CN | claimed |
| EP-1208165-B1 | PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS | PPG IND OHIO INC (US) | 2007-12-19 | — | — | EP | claimed |
| EP-1208164-B1 | PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS | PPG IND OHIO INC (US) | 2007-10-24 | — | — | EP | claimed |
| CN-1795245-A | Adhesion enhancing coating composition, process for using and coated or laminated articles produced | TRANSITIONS OPTICAL INC (US) | 2006-06-28 | — | — | CN | claimed |
| US-6984262-B2 | Adhesion enhancing coating composition, process for using and articles produced | TRANSITIONS OPTICAL, INC. (US) | 2006-01-10 | — | — | US | claimed |
| US-12104038-B2 | Silica reinforced rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-10-01 | — | — | US | disclosed |
| CN-114981349-B | Method for preparing modified filler, composition and article containing the modified filler | PPG工业俄亥俄公司 | 2024-07-26 | — | — | CN | disclosed |
| US-11708475-B2 | Method for preparing modified filler, compositions and articles containing same | PPG INDUSTRIES OHIO, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230174743-A1 | TIRE TREAD RUBBER COMPOSITION COMPRISING RICE HUSK ASH SILICA | THE GOODYEAR TIRE & RUBBER COMPANY | 2023-06-08 | — | — | US | disclosed |
| EP-4190589-A1 | TIRE TREAD RUBBER COMPOSITION COMPRISING RICE HUSK ASH SILICA | The Goodyear Tire & Rubber Company (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20230033274-A1 | METHOD FOR PREPARING MODIFIED FILLER, COMPOSITIONS AND ARTICLES CONTAINING SAME | PPG INDUSTRIES OHIO, INC. (US) | 2023-02-02 | — | — | US | disclosed |
| EP-4077525-A1 | METHOD FOR PREPARING MODIFIED FILLER, COMPOSITIONS AND ARTICLES CONTAINING SAME | PPG Industries Ohio Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| US-7857990-B2 | Calcium hypochlorite composition | PPG INDUSTRIES OHIO, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| CN-100513501-C | Adhesion enhancing coating compositions, methods of using the same and coated or laminated articles produced therefrom | TRANSITIONS OPTICAL INC (US) | 2009-07-15 | — | — | CN | disclosed |
| US-20080067468-A1 | CALCIUM HYPOCHLORITE COMPOSITION | PPG INDUSTRIES OHIO, INC. (US) | 2008-03-20 | — | — | US | disclosed |
| CN-1795245-A | Adhesion enhancing coating composition, process for using and coated or laminated articles produced | TRANSITIONS OPTICAL INC (US) | 2006-06-28 | — | — | CN | disclosed |
| CN-1522796-A | Catalyst for the production of alpha-olefin and alpha-olefin production method thereof | 出光石油化学株式会社 | 2004-08-25 | — | — | CN | disclosed |
| CN-1048502-C | Olefin polymerization catalysts and methods of olefin polymerization | MITSUI PETROCHEMICAL IND (JP) | 2000-01-19 | — | — | CN | disclosed |
| CN-1100429-A | Olefin polymerization catalysts and methods of olefin polymerization | MITSUI PETROCHEMICAL IND (JP) | 1995-03-22 | — | — | CN | disclosed |