Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TYMS | P04818 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3622578 | 1.00 | MAOA (0.64) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL1366362 | 0.83 | KMT2A (0.48) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL1366359 | 0.83 | KMT2A (0.48) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL15368900 | 0.81 | MAOA (0.46) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL11522370 | 0.79 | MAOA (1.00) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL6353583 | 0.79 | MAOA (1.00) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL22284 | 0.79 | MAOA (1.00) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL29448271 | 0.79 | MAOA (1.00) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL6903786 | 0.79 | MAOA (1.00) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL3628521 | 0.79 | MAOA (0.56) | MAOAMAOBALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393775-B1 | METHOD FOR PRODUCING 2-HALOGENOMETHYLPHENYL ACETIC ACID DERIVATIVES | BASF SE (DE) | 2014-06-25 | — | — | EP | disclosed |
| US-8575366-B2 | Method for producing 2-halogenomethylphenyl acetic acid derivatives | BASF SE (DE) | 2013-11-05 | — | — | US | disclosed |
| EP-2393775-A2 | METHOD FOR PRODUCING 2-HALOGENOMETHYLPHENYL ACETIC ACID DERIVATIVES | BASF SE (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-20110295022-A1 | Method for producing 2-halogenomethylphenyl acetic acid derivatives | BASE SE (DE) | 2011-12-01 | — | — | US | disclosed |
| WO-2010089267-A2 | METHOD FOR PRODUCING 2-HALOGENOMETHYLPHENYL ACETIC ACID DERIVATIVES | BASF SE (DE) | 2010-08-12 | — | — | WO | disclosed |
| US-6465457-B1 | CONTROLLING PATHOGENS ON PLANTS OR SEEDS | ZENECA LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |
| EP-0711751-B1 | Process for the preparation of intermediates for oxime ether- or 2-phenyl-3-methyl propenoate-fungicides | ZENECA LTD (GB) | 1999-10-20 | — | — | EP | disclosed |
| US-5939563-A | FUNGICIDES | ZENECA LIMITED (GB) | 1999-08-17 | — | — | US | disclosed |
| US-5777162-A | Intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1998-07-07 | — | — | US | disclosed |
| US-5585513-A | CHEMICAL INTERMEDIATES | ZENECA LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| EP-0711751-A1 | Process for the preparation of intermediates for oxime ether- or 2-phenyl-3-methyl propenoate-fungicides | ZENECA LIMITED (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1993007116-A1 | FUNGICIDES | ZENECA LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295022-A1 | Method for producing 2-halogenomethylphenyl acetic acid derivatives | HACL2, AKR7A2, ALAD | MAOA 237/4885MAOB 512/4885ALDH1A1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.