Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364370 | 0.83 | — | — | |
| SCHEMBL362408 | 0.78 | NFE2L2 (0.35) | KIF11 | |
| SCHEMBL4461018 | 0.75 | KCNN4 (0.47) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL440368 | 0.70 | KIF11 (0.41) | KMT2AALDH1A1LMNAHTTKIF11 | |
| SCHEMBL365204 | 0.68 | FFAR1 (0.31) | — | |
| SCHEMBL363298 | 0.67 | EGFR (0.32) | KMT2AMAPTHTTHPGDKIF11 | |
| SCHEMBL362087 | 0.67 | ALDH1A1 (0.31) | ALDH1A1GLAHPGDCTSC | |
| SCHEMBL370168 | 0.64 | CYP19A1 (0.33) | KIF11CYP19A1MKNK2 | |
| SCHEMBL11955162 | 0.64 | MKNK1 (0.38) | ALDH1A1MAPTKDM4EMKNK1MKNK2 | |
| SCHEMBL364699 | 0.63 | GAA (0.36) | KMT2AALDH1A1MAPTHPGDKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |