SCHEMBL3624341

SCHEMBL3624341

CC(C)(C)c1ccc(-c2cc(-c3ccc(C(C)(C)C)cc3)nc(Cl)n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
KMT2A Q03164 5/20 0.55
MEN1 O00255 4/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
HPGD P15428 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
MAPT P10636 3/20 0.55
KDM4E B2RXH2 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
KIF11 P52732 3/20 0.45
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
NPSR1 Q6W5P4 2/20 0.43
TNF P01375 1/20 0.41
NOD1 Q9Y239 1/20 0.41
DHODH Q02127 1/20 0.41
TDO2 P48775 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
MITF O75030 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1012956 0.91 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1L3MBTL1HPGD
SCHEMBL29389980 0.91 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1L3MBTL1HPGD
SCHEMBL4815491 0.88 NPC1 (0.46) ALDH1A1KMT2AMEN1L3MBTL1HPGD
SCHEMBL18216910 0.82 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1L3MBTL1HPGD
SCHEMBL23928344 0.82 MEN1 (0.47) ALDH1A1KMT2AMEN1L3MBTL1HPGD
SCHEMBL17413751 0.79 NPC1 (0.53) ALDH1A1KMT2AMEN1L3MBTL1HPGD
SCHEMBL1013065 0.78 ALDH1A1 (0.42) ALDH1A1KMT2AMEN1L3MBTL1HPGD
SCHEMBL783069 0.78 RAB9A (0.60) ALDH1A1KMT2AMEN1L3MBTL1HPGD
SCHEMBL19193784 0.78 RAB9A (0.60) ALDH1A1KMT2AMEN1L3MBTL1HPGD
SCHEMBL15745465 0.77 MEN1 (0.59) ALDH1A1KMT2AMEN1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230403927-A1 AROMATIC COMPOUNDS UDC IRELAND LTD (IE) 2023-12-14 US disclosed
US-20230403927-A1 AROMATIC COMPOUNDS UDC IRELAND LTD (IE) 2023-12-14 US disclosed
US-11800787-B2 Metal complexes UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11800787-B2 Metal complexes UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11024815-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-06-01 US disclosed
EP-3254317-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-07-31 EP disclosed
EP-3160976-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-07-24 EP disclosed
US-20180026209-A1 Metal Complexes MERCK PATENT GMBH (DE) 2018-01-25 US disclosed
US-20180026209-A1 Metal Complexes MERCK PATENT GMBH (DE) 2018-01-25 US disclosed
US-9853228-B2 Metal complexes MERCK PATENT GMBH (DE) 2017-12-26 US disclosed
US-20170141329-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2017-05-18 US disclosed
US-20170141329-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2017-05-18 US disclosed
WO-2016124304-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2016-08-11 WO disclosed
WO-2016015815-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2016-02-04 WO disclosed
US-8608986-B2 Metal complex, polymer compound and device containing those SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-17 US disclosed
EP-2128168-B1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE SUMITOMO CHEMICAL CO (JP) 2013-11-06 EP disclosed
EP-2128168-B1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE SUMITOMO CHEMICAL CO (JP) 2013-11-06 EP disclosed
US-20100019669-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-28 US disclosed
US-20100019669-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-28 US disclosed
EP-2128168-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE Sumitomo Chemical Company, Limited (JP) 2009-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11024815-B2 Metal complexes EXOC4, EXOC3, TIMCC ALDH1A1 2742/4885KMT2A 3131/4885MEN1 2821/4885
US-20230403927-A1 AROMATIC COMPOUNDS TYR, CTCF, MITF ALDH1A1 1461/4885KMT2A 1055/4885MEN1 2141/4885
US-20170141329-A1 METAL COMPLEXES AP1M1, SOD1, AP3M1 ALDH1A1 3771/4885KMT2A 2648/4885MEN1 766/4885
US-20100019669-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE AP1M1, MRPL21, C1R ALDH1A1 4138/4885KMT2A 1105/4885MEN1 38/4885
US-20180026209-A1 Metal Complexes AP3M1, AP2M1, SOD1 ALDH1A1 2597/4885KMT2A 3024/4885MEN1 1212/4885
US-11800787-B2 Metal complexes AP1M1, SOD1, AP3M1 ALDH1A1 3771/4885KMT2A 2648/4885MEN1 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.